Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)
First Claim
Patent Images
1. An isolated monoclonal antibody that binds human DEC-205 (SEQ ID NO:
- 1) comprising a heavy and a light chain variable region, wherein the heavy or light chain variable region sequences comprise;
(a) SEQ ID NOs;
4 or 10, respectively;
(b) SEQ ID NOs;
16 or 22, respectively;
(c) SEQ ID NOs;
28 or 34, respectively;
(d) SEQ ID NOs;
40 or 46, respectively;
(e) SEQ ID NOs;
52 or 58, respectively;
or(f) SEQ ID NOs;
76 or 82, respectively.
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Abstract
Isolated monoclonal antibodies which bind to human DEC-205 and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
41 Citations
5 Claims
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1. An isolated monoclonal antibody that binds human DEC-205 (SEQ ID NO:
- 1) comprising a heavy and a light chain variable region, wherein the heavy or light chain variable region sequences comprise;
(a) SEQ ID NOs;
4 or 10, respectively;(b) SEQ ID NOs;
16 or 22, respectively;(c) SEQ ID NOs;
28 or 34, respectively;(d) SEQ ID NOs;
40 or 46, respectively;(e) SEQ ID NOs;
52 or 58, respectively;
or(f) SEQ ID NOs;
76 or 82, respectively. - View Dependent Claims (2, 3, 4, 5)
- 1) comprising a heavy and a light chain variable region, wherein the heavy or light chain variable region sequences comprise;
Specification