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Extraction of materials from regions of interest in a sample

  • US 9,625,355 B2
  • Filed: 12/01/2014
  • Issued: 04/18/2017
  • Est. Priority Date: 12/01/2014
  • Status: Active Grant
First Claim
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1. A system for extracting material from a region of interest, comprising:

  • a fluid delivery base;

    a first channel within the fluid delivery base and open to a first channel end at a sample-facing surface of the fluid delivery base, wherein the first channel comprises a first channel opening configured to couple to a fluid inlet to fluidically couple the fluid inlet to the first channel end;

    a second channel within the fluid delivery base and terminating at a second channel end at the sample-facing surface of the fluid delivery base, wherein the second channel comprises a second channel opening configured to couple to a fluid outlet to fluidically couple the fluid outlet to the second channel end;

    an adaptor coupled to the first channel opening and the second channel opening, wherein the adaptor comprises an interior channel that couples the first channel end to the fluid inlet;

    a gasket coupled to the sample-facing surface and comprising a gasket opening aligned with an area of the sample-facing surface comprising the first channel end and the second channel end;

    a support comprising a sample-supporting surface configured to hold a sample against the gasket and an opposing surface; and

    an alignment member coupled to the opposing surface, wherein the fluid delivery base is separable from the support and configured to move along a plane of the sample-supporting surface to align with the alignment member.

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