Devices for therapeutic vascular procedures

• US 9,629,635 B2
• Filed: 04/10/2015
• Issued: 04/25/2017
• Est. Priority Date: 04/14/2014
• Status: Active Grant

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Sequent Medical, Inc. (Terumo Corporation)
• Inventors: Thompson, James M, Hewitt, Todd J, Merritt, Brian, Patterson, William R, Plaza, Claudio, Tran, Hung P
• Primary Examiner(s): Woo, Julian W
• Application Number:
  US14/684,212
• Publication Number:
  US 20160249935A1
• Time in Patent Office: 746 Days
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61F 2310/00149 Platinum or Pt-based alloys
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less

Abstract

Methods and devices for removing a thrombus are described. The device includes an expandable cylindrical structure made of wires and a self-expanding permeable shell located at the distal end of the cylindrical structure. Methods and devices for treating a cerebral aneurysm are described. The device may include a distal self-expanding resilient permeable shell, a proximal self-expanding resilient permeable shell, and an elongate support member positioned between the distal and proximal permeable shells. The elongate support member may be rigid or may be a coil, such as an extension spring. The distal and proximal permeable shells may be made from a plurality of braided filaments, the shells having different pore sizes. The device may also be a braided implant with a force biasing component, such as a coil or generally circular extension, attached to its distal end.

Claims

1. A method for treating a cerebral aneurysm, comprising the steps of:

providing an implant structure comprising;

a self-expanding resilient permeable shell having a proximal end, a distal end, and a longitudinal axis, the shell comprising a plurality of elongate resilient filaments having a braided structure, wherein the plurality of filaments are secured at least at one of the proximal end or the distal end thereof;

a force biasing member secured at the distal end of the self-expanding resilient permeable shell;

wherein the permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded deployed state with a globular, axially shortened configuration relative to the radially constrained state, the permeable shell having a plurality of openings formed between the braided filaments; and

wherein the force biasing member has a linear, straightened shape configured for delivery within a microcatheter and an expanded state after delivery from the microcatheter;

advancing the implant structure within a microcatheter to a region near the cerebral aneurysm;

deploying the implant structure within the cerebral aneurysm, the force biasing member positioned near a dome of the cerebral aneurysm and assuming the expanded state and the permeable shell assuming the expanded deployed state within the cerebral aneurysm; and

withdrawing the microcatheter from the region near the cerebral aneurysm after deploying the implant structure.

2. The method of claim 1, wherein the force biasing member pushes the permeable shell against the opening of the cerebral aneurysm.

3. The method of claim 1, wherein the force biasing member is configured to place a bias on the permeable shell when the permeable shell is in the expanded deployed state within an aneurysm.

4. The method of claim 1, wherein the force biasing member, when at least partially compressed in an axial direction, applies an axial bias of at least 0.27 grams.

5. The method of claim 1, wherein the force biasing member, when at least partially compressed in an axial direction, applies an axial bias of at least 2.67 grams.

6. The method of claim 1, wherein the force biasing member, when at least partially compressed in an axial direction, applies an axial bias of at least 16.6 grams.

7. The method of claim 1, wherein the force biasing member is configured to conform to a three-dimensional framing shape.

8. The method of claim 1, wherein the force biasing member is formed from wire comprising platinum.

9. The method of claim 1, wherein the plurality of filaments are secured at the distal end of the permeable shell, wherein a distal region of at least some of the plurality of filaments extend beyond the distal end of the permeable shell and form an extension having a generally circular shape, and wherein the force biasing member comprises the extension having the generally circular shape when expanded.

10. The method of claim 9, wherein the plurality of filaments are secured by a cylindrical hub having a proximal and distal end, and wherein the extension extends from the distal end of the cylindrical hub.

11. The method of claim 9, wherein the distal regions of the at least some of the plurality of filaments forming the extension are braided.

12. The method of claim 11, wherein the braided distal regions are at least partially unraveled.

13. The method of claim 9, wherein the distal regions of the at least some of the plurality of filaments forming the extension are partially braided.