Reinforcement device with dissolvable layer and its use

• US 9,629,703 B2
• Filed: 10/31/2016
• Issued: 04/25/2017
• Est. Priority Date: 05/20/2010
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Paul, Martin G.
• Primary Examiner(s): FISHBACK, ASHLEY LAUREN
• Application Number:
  US15/339,010
• Publication Number:
  US 20170042655A1
• Time in Patent Office: 176 Days
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2002/0068 having a special mesh pattern
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures

Abstract

A reinforcement device for reinforcing tissues having one or more structural deficiencies includes a longitudinally-extending reinforcing layer for treating the structural deficiency, a plurality of spiked naps distributed across the reinforcing layer and projecting therefrom for adhering to the tissue, and a dissolvable matrix layer covering at least a portion of the reinforcing layer and a portion of the plurality of spiked naps. The matrix layer increases the time before the spiked naps substantially adhere to the tissue, thereby allowing the practitioner additional time to position the reinforcement device.

Claims

1. A method for reinforcing tissues having one or more structural deficiencies, comprising:

contacting tissue with a reinforcement device including a longitudinally extending reinforcing layer for treating the structural deficiency, the layer having a first face and a second face and the layer including a porous knit mesh formed of a monofilament yarn;

a plurality of naps distributed across at least the first face and projecting therefrom for adhering to tissue; and

a dissolvable matrix layer covering at least a portion of at least the second face of the reinforcing layer opposite the naps; and

holding the reinforcement device on the tissue until at least a portion of the dissolvable matrix layer dissolves.

2. The method of claim 1, further comprising adding a liquid solvent at the same time the reinforcement device is being held on the tissue.

3. The method of claim 2, wherein the liquid solvent is saline.

4. The method of claim 1, wherein the naps comprise a biocompatible polymer selected from one or more of polypropylene, polymers of p-dioxanone, polyglycolides, polyorthoesters, polymers of trimethylene carbonate, stereocopolymers of L-lactic acid and D-lactic acid, homopolymers of L-lactic acid, copolymers of lactic acid and a compatible comonomer.

5. The method of claim 1, wherein the dissolvable layer comprises one or more of a biodegradable component, an antibacterial component, an excipient, therapeutic drug, a plasticizer, and a binder component.

6. The method of claim 1, wherein the reinforcement device further comprises a bioadhesive layer.

7. A method for reinforcing tissues having one or more structural deficiencies, comprising:

contacting tissue with a reinforcement device including a longitudinally extending reinforcing layer for treating the structural deficiency, the layer having a first face and a second face;

a plurality of naps distributed across at least the first face and projecting therefrom for adhering to tissue; and

a dissolvable layer covering the plurality of naps, the layer adapted to increase the time before the naps substantially adhere to the tissue; and

holding the reinforcement device on the tissue until at least a portion of the dissolvable matrix layer dissolves.

8. The method of claim 7, further comprising the step of adding a liquid solvent at the same time the reinforcement device is being held on the tissue.

9. The method of claim 8, wherein the liquid solvent is saline.

10. The method of claim 7, wherein the reinforcing layer comprises a three-dimensional and open-worked, porous knit.

11. The method of claim 7, wherein the naps comprise a biocompatible polymer selected from one or more of polypropylene, polymers of p-dioxanone, polyglycolides, polyorthoesters, polymers of trimethylene carbonate, stereocopolymers of L-lactic acid and D-lactic acid, homopolymers of L-lactic acid, copolymers of lactic acid and a compatible comonomer.

12. The method of claim 7, wherein the dissolvable layer comprises one or more of a biodegradable component, an antibacterial component, an excipient, a therapeutic drug, a plasticizer, and a binder component.

13. The method of claim 7, wherein the reinforcement device further comprises a bioadhesive layer.

14. A method for reinforcing tissues having one or more structural deficiencies, comprising:

contacting tissue with a reinforcement device including a longitudinally extending reinforcing layer for treating the structural deficiency, the layer having a first face and a second face;

a plurality of naps distributed across at least the first face and projecting therefrom for adhering to tissue; and

a dissolvable matrix layer covering at least a portion of at least the second face of the reinforcing layer opposite the naps; and

holding the reinforcement device on the tissue until at least a portion of the dissolvable matrix layer dissolves.

15. The method of claim 14, further comprising the step of adding a liquid solvent at the same time the reinforcement device is being held on the tissue.

16. The method of claim 15, wherein the liquid solvent is saline.

17. The method of claim 14, wherein the reinforcing layer comprises a three-dimensional and open-worked, porous knit.

18. The method of claim 14, wherein the naps comprise a biocompatible polymer.

19. The method of claim 14, wherein the dissolvable matrix layer comprises one or more of a biodegradable component, an antibacterial component, an excipient, therapeutic drug, a plasticizer, and a binder component.

20. The method of claim 14, further comprising a bioadhesive layer.