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Single crystal quartz chips for protein crystallization and X-ray diffraction data collection and related methods

  • US 9,632,042 B2
  • Filed: 09/30/2014
  • Issued: 04/25/2017
  • Est. Priority Date: 10/25/2013
  • Status: Active Grant
First Claim
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1. A crystallization device for in situ x-ray diffraction of biological samples, comprising:

  • a first flat plate made of single crystal quartz, single crystal silicon or single crystal sapphire and having a plurality of wells defined on the plate;

    a second flat plate made of single crystal quartz, single crystal silicon or single crystal sapphire disposed to cover the first flat plate with an air gap between the first and second plates; and

    a sealing material disposed between the first plate and the second plate to seal them together to define a sealed space formed by the air gap for holding the samples.

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