Delivery of therapeutics to treat aneurysms

• US 9,636,439 B2
• Filed: 04/03/2008
• Issued: 05/02/2017
• Est. Priority Date: 09/19/2003
• Status: Expired due to Fees

• Current Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Original Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Inventors: Chu, Jack, Erickson, Dave, Ganesan, Prema, Morris, Jonathan
• Primary Examiner(s): SCHALL, MATTHEW WAYNE
• Application Number:
  US12/062,245
• Publication Number:
  US 20080183158A1
• Time in Patent Office: 3,316 Days
• Field of Search: 623 143, 623 142, 623 115, 623 11, 623 135, 606213, 604 9901, 604 60, 6048911
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/077 having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61L 2300/00 Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
• CPC Class Codes: A61L 2430/36 for embolization or occlusion, e.g. vaso-occlusive compositions or devices artificial blood vessels A61L27/507
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a reservoir and delivery means in a localized, and, in some embodiments, time-released regimen, to treat, limit and reduce the severity of the aneurysm.

Claims

1. An aneurismal tissue treatment system comprising:

a stent graft adapted for placement within a vessel lumen adjacent an aneurismal site; and

at least one implantable therapeutic agent delivery reservoir adapted to be implanted external to said vessel lumen and further adapted to deliver a carrier comprising at least one therapeutic agent from said reservoir to said aneurismal site over time wherein said reservoir comprises said carrier and said at least one therapeutic agent within said reservoir,

wherein said implantable therapeutic agent delivery reservoir comprises a pump.

2. The aneurismal tissue treatment system according to claim 1 wherein said pump is mechanical, electrical, or osmotic.

3. An aneurismal tissue treatment system, comprising:

a stent graft adapted for placement within a vessel lumen adjacent an aneurismal site; and

at least one implantable therapeutic agent delivery reservoir adapted to be implanted external to said vessel lumen and further adapted to deliver a carrier comprising at least one therapeutic agent from said reservoir to said aneurismal site over time wherein said reservoir comprises said carrier and said at least one therapeutic agent within said reservoir,

wherein said at least one implantable therapeutic agent delivery reservoir delivers said at least one therapeutic agent to said aneurismal tissue by means of a pump and tubing for the treatment of said aneurismal tissue.