Implantable cardioverter-defibrillator (ICD) system having multiple common polarity extravascular defibrillation electrodes

• US 9,636,512 B2
• Filed: 11/04/2015
• Issued: 05/02/2017
• Est. Priority Date: 11/05/2014
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Cinbis, Can, Nikolski, Vladimir P., Cao, Jian, Carney, James K., O'Brien, Richard J., Thompson-Nauman, Amy E., Christie, Melissa G. T.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US14/932,311
• Publication Number:
  US 20160121130A1
• Time in Patent Office: 545 Days
• CPC Class Codes: A61N 1/0587 Epicardial electrode systems; Endocardial electrodes piercing the pericardium
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/3918 characterised by shock pathway, e.g. by electrode configuration
• CPC Class Codes: A61N 1/39622 Pacing therapy
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

This disclosure provides an extravascular ICD system and method for defibrillating a heart of a patient. The extravascular ICD system includes multiple extravascular electrical stimulation leads or lead segments located in close proximity to one another and having respective defibrillation electrodes. The ICD system utilizes the multiple defibrillation electrodes to form an extravascular electrode vector that may result a reduction in the shock impedance and/or a reduction in the DFT compared to extravascular ICD systems that include only a single extravascular defibrillation electrode. An ICD of the system may, for example, deliver a defibrillation shock using an electrode vector in which a first polarity of the electrode vector is formed by electrically coupling first and second defibrillation electrodes of first and second leads, respectively, to the therapy circuitry and a second polarity of the electrode vector is formed by electrically coupling a housing of the ICD to the therapy circuitry.

Claims

1. An implantable cardioverter-defibrillator (ICD) system comprising:

an ICD implanted in a patient under the skin and outside of the ribcage, the ICD including;

a housing;

a power source within the housing;

a therapy module within the housing that includes at least one defibrillation capacitor; and

a control module within the housing;

a first electrical stimulation lead having a proximal portion coupled to the ICD and a distal portion having a first defibrillation electrode configured to deliver a defibrillation shock from a substernal location to a heart of the patient, the substernal location being at least partially within the anterior mediastinum; and

a second electrical stimulation lead having a proximal portion coupled to the ICD and a distal portion having a second defibrillation electrode configured to deliver a defibrillation shock to the heart of the patient,

wherein the control module is configured to couple the at least one defibrillation capacitor to an electrode vector to deliver a high voltage shock to the heart of the patient, wherein the control module couples the at least one defibrillation capacitor to the first and second defibrillation electrodes concurrently to form a first polarity of the electrode vector and to the housing of the ICD to form a second polarity of the electrical vector.

2. The ICD system of claim 1, wherein the second defibrillation electrode is configured to deliver the defibrillation shock from the substernal location to the heart of the patient.

3. The ICD system of claim 2, wherein one of the first defibrillation electrode includes a plurality of separate electrodes that collectively form the first defibrillation electrode.

4. The ICD system of claim 1, wherein

the first electrical stimulation lead includes one or more electrodes separate from the first defibrillation electrode to sense electrical signals of the heart at the substernal location;

and

the ICD further includes a sensing module that obtains the sensed electrical signals of the heart sensed at the substernal location, wherein the control module analyzes the signals output from the sensing module to detect a tachyarrhythmia.

5. The ICD system of claim 1, wherein at least one of the first electrical stimulation lead and the second electrical stimulation lead includes one or more electrodes separate from the first and second defibrillation electrodes to deliver pacing pulses from the substernal location to the heart.

6. The ICD system of claim 1, wherein the control module is configured to couple the at least one defibrillation capacitor to the first defibrillation electrode and the second defibrillation electrode in parallel to form the first polarity of the electrode vector.

7. The ICD system of claim 6, wherein the therapy module includes a single high voltage output that electrically couples to the first defibrillation electrode and the second defibrillation electrode.

8. The ICD system of claim 6, wherein the therapy module includes a first high voltage output and a second high voltage output that are both associated with the first polarity, wherein the control module concurrently couples the first and second high voltage outputs to the first and the second defibrillation electrodes, respectively, to form the first polarity of the electrode vector.

9. The ICD system of claim 1, wherein the control module is configured to couple the at least one defibrillation capacitor to the first defibrillation electrode and the second defibrillation electrode in series to form the first polarity of the electrode vector.

10. The ICD system of claim 1, wherein the second defibrillation electrode is configured to deliver a defibrillation shock from the substernal location to the heart of the patient, the second defibrillation electrode being implanted in the substernal location.

11. The ICD system of claim 10, wherein the first electrical stimulation lead and the second electrical stimulation lead are separated from one another underneath the sternum by a distance.

12. The ICD system of claim 11, wherein the distance is between approximately 10-40 millimeters (mm).

13. The ICD system of claim 11, wherein the distance is between approximately 15-30 millimeters (mm).

14. The ICD system of claim 11, wherein the distance is between approximately 20-25 millimeters (mm).

15. The ICD system of claim 1, wherein the second defibrillation electrode is configured to deliver a defibrillation shock from an extra-thoracic location to the heart of the patient, the second defibrillation electrode being implanted extra-thoracically.

16. A method for extravascularly defibrillating a heart of a patient, the method comprising:

obtaining electrical signals sensed from a substernal location via one or more electrodes in the substernal location;

processing the electrical signals to detect a tachyarrhythmia;

charging one or more defibrillation capacitors in response to detecting the tachyarrhythmia;

electrically coupling the one or more defibrillation capacitors to an electrode vector to deliver a defibrillation therapy to the heart of the patient, the electrode vector including a first polarity formed by a first defibrillation electrode of a first electrical stimulation lead and a second defibrillation electrode of a second electrical stimulation lead and a second polarity formed by a housing of an implantable cardioverter-defibrillator (ICD), wherein the first defibrillation electrode is implanted at least partially in the substernal location.

17. The method of claim 16, further comprising delivering one or more sequences of anti-tachycardia pacing (ATP) pulses via the one or more electrodes in the substernal location.

18. The method of claim 16, wherein electrically coupling the one or more defibrillation capacitors to an electrode vector comprises electrically coupling the one or more defibrillation capacitors to the first defibrillation electrode and the second defibrillation electrode in parallel to form the first polarity of the electrode vector.

19. The method of claim 16, wherein electrically coupling the one or more defibrillation capacitors to an electrode vector comprises electrically coupling the one or more defibrillation capacitors to the first defibrillation electrode and the second defibrillation electrode in series to form the first polarity of the electrode vector.

20. The method of claim 16, wherein electrically coupling the one or more defibrillation capacitors to an electrode vector comprises electrically coupling a first high voltage output and a second high voltage output that are both associated with the first polarity, wherein the control module concurrently couples the first and second high voltage outputs to the first and the second defibrillation electrodes, respectively, to form the first polarity of the electrode vector.

21. An implantable cardioverter-defibrillator (ICD) system comprising:

an ICD implanted in a patient under the skin and outside of the ribcage, the ICD including;

a housing;

a power source within the housing;

a therapy module within the housing that includes at least one defibrillation capacitor; and

a control module within the housing;

an electrical stimulation lead having a lead body that includes a proximal portion configured to be coupled to the ICD and a distal portion that includes a first lead segment having a first defibrillation electrode configured to deliver a defibrillation shock from a substernal location to a heart of the patient, the first electrode being implanted at least partially along a posterior side of a sternum of the patient in the substernal location, and second lead segment having a second defibrillation electrode configured to deliver a defibrillation shock to the heart of the patient,

wherein the control module is configured to couple the at least one defibrillation capacitor to an electrode vector to deliver a high voltage shock to the heart of the patient, wherein the control module couples the at least one defibrillation capacitor to the first and second defibrillation electrodes concurrently to form a first polarity of the electrode vector and to the housing of the ICD to form a second polarity of the electrical vector.

22. The ICD system of claim 21, wherein the control module is reconfigured to couple the at least one defibrillation capacitor to a second electrode vector to deliver a high voltage shock to the heart of the patient, wherein the control module couples the at least one defibrillation capacitor to the first defibrillation electrode to form a first polarity of the second electrode vector and to one of the housing of the ICD and the second defibrillation electrode to form a second polarity of the second electrical vector.