Wound care dressing

• US 9,643,001 B2
• Filed: 02/02/2016
• Issued: 05/09/2017
• Est. Priority Date: 04/14/2015
• Status: Active Grant

• Current Assignee: Taiwan Textile Research Institute
• Original Assignee: Taiwan Textile Research Institute
• Inventors: Wu, Ting-Yu, Chang, Ting-Yu
• Primary Examiner(s): VOORHEES, CATHERINE M
• Application Number:
  US15/013,997
• Publication Number:
  US 20160303362A1
• Time in Patent Office: 462 Days
• CPC Class Codes: A61L 15/42 Use of materials characterised by their function or physical properties liquid bandages A61L26/00
• CPC Class Codes: A61L 15/44 Medicaments
• CPC Class Codes: A61L 15/60 Liquid-swellable gel-forming materials, e.g. super-absorbents
• CPC Class Codes: A61L 2300/102 Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
• CPC Class Codes: A61L 2300/104 Silver, e.g. silver sulfadiazine
• CPC Class Codes: A61L 2430/34 for soft tissue reconstruction
• CPC Class Codes: A61N 1/0468 Specially adapted for promoting wound healing
• CPC Class Codes: A61N 1/0496 characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
• CPC Class Codes: A61N 1/205 for promoting a biological process

Abstract

A wound care dressing is provided, including a hydrophobic base fabric, a plurality of electrode pairs, a plurality of hydrogel layers, and a waterproof thin film. The hydrophobic base fabric has a first surface and a second surface opposite to each other. The electrode pairs are arranged in an array and disposed on the first surface of the hydrophobic base fabric. The hydrogel layers are not in contact with one other, and each hydrogel layer covers a top surface and side walls of each electrode in the electrode pairs. After the hydrogel layers are in contact with a wound and absorb tissue fluid from the wound, the hydrogel layers form a restrictive electronic cycling channel with the electrode pairs to establish a plurality of bioelectric fields promoting wound healing on a surface of the wound. The waterproof thin film is disposed on the second surface of the hydrophobic base fabric.

Claims

1. A wound care dressing, comprising:

a hydrophobic base fabric having a first surface and a second surface opposite to each other;

a plurality of electrode pairs disposed on the first surface of the hydrophobic base fabric, wherein the electrode pairs are arranged in an array;

a plurality of hydrogel layers, wherein the hydrogel layers are not in contact with one another, and each of the hydrogel layers covers a top surface and sidewalls of each of the electrodes in the electrode pairs, wherein after the hydrogel layers are in contact with a wound and absorb a tissue fluid from the wound, the hydrogel layers are adapted to form a restrictive electronic cycling channel with the electrode pairs to establish a plurality of bioelectric fields promoting wound healing on a surface of the wound; and

a waterproof thin film disposed on the second surface of the hydrophobic base fabric,

wherein each of the electrode pairs comprises;

a first electrode formed by a first active substance and a first conductive carbon paste, wherein based on a total weight of the first active substance and the first conductive carbon paste, a content of the first conductive carbon paste is 5 wt % to 80 wt %; and

a second electrode formed by a second active substance and a second conductive carbon paste, wherein based on a total weight of the second active substance and the second conductive carbon paste, a content of the second conductive carbon paste is 5 wt % to 80 wt %, and when the wound care dressing is applied on the wound, the second electrode and the first electrode generate a current conduction via at least the hydrogel layers.

2. The wound care dressing of claim 1, wherein a material of the first active substance and a material of the second active substance comprise zinc, copper, silver, carbon, silver oxide, magnesium, manganese, nickel, or a combination thereof.

3. The wound care dressing of claim 1, wherein the first electrode and the second electrode are respectively a symmetric semicircular electrode having a same size, a distance between the first electrode and the second electrode is 1.8 mm to 2.2 mm, and a radius of the semicircular electrode is 4.9 mm to 5.1 mm.

4. The wound care dressing of claim 1, wherein the first electrode and the second electrode are respectively a circular electrode having a same size.

5. The wound care dressing of claim 4, wherein a diameter of the circular electrode is 9.8 mm to 10.2 mm and a distance between center points of adjacent first and second electrodes is 11 mm to 15 mm.

6. The wound care dressing of claim 4, wherein a diameter of the circular electrode is 4.8 mm to 5.2 mm and a distance between center points of adjacent first and second electrodes is 6 mm to 10 mm.

7. The wound care dressing of claim 1, wherein each of the hydrogel layers is a UV curing layer comprising:

a main agent system comprising acrylic acid, alkyl acrylate, fluoroalkyl ester, methacrylic acid, methyl methacrylate, 2-hydroxyethyl methacrylate, or glycidyl methacrylate;

a UV curing initiator comprising α

-aminoketone, α

-hydrocarbon ketone, acyl phosphate oxide, benzoin diethyl ether, benzophenone, a cationic photoinitiator, or benzoyl formate; and

a polyol plasticizer comprising glycol, polyvinyl alcohol, polyvinylpyrrolidone, or glycerol.

8. The wound care dressing of claim 1, wherein a thickness of each of the hydrogel layers is 1 mm to 2 mm.

9. The wound care dressing of claim 1, wherein a thickness of each of the electrodes in the electrode pairs is 1.5 mm to 3 mm.

10. The wound care dressing of claim 1, wherein an aperture of the hydrophobic base fabric is 5 μ

m to 40 μ

m, and a thickness of the hydrophobic base fabric is 0.5 mm to 1 mm.

11. The wound care dressing of claim 1, wherein in the restrictive electronic cycling channel, a discharge voltage of the restrictive electronic cycling channel formed by the hydrogel layers with the electrode pairs is 0.6 V to 0.9 V, and a current of the restrictive electronic cycling channel formed by the hydrogel layers with the electrode pairs is 0.1 amperes to 0.3 amperes.