Pumping cassette

• US 9,649,418 B2
• Filed: 01/17/2012
• Issued: 05/16/2017
• Est. Priority Date: 02/27/2007
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Wilt, Michael J., Grant, Kevin L., Dale, James D., Tracey, Brian D., Demers, Jason A.
• Primary Examiner(s): Hamo, Patrick
• Application Number:
  US13/352,250
• Publication Number:
  US 20120207627A1
• Time in Patent Office: 1,946 Days
• Field of Search: 4174772, 210252, 210645, 604 611, 604151
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1639 linked by membranes
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1664 with temperature control
• CPC Class Codes: A61M 1/1666 by dissolving solids
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/268 the displacement member being flexible, e.g. membranes, diaphragms or bladders
• CPC Class Codes: A61M 60/37 Haemodialysis, haemofiltration or diafiltration
• CPC Class Codes: A61M 60/427 : the force acting on the blood contacting member being hydraulic or pneumatic
• CPC Class Codes: A61M 60/43 : using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/837 : Aspects of flexible displacement members, e.g. shapes or materials
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/849 : Disposable parts
• CPC Class Codes: A61M 60/851 : Valves
• CPC Class Codes: A61M 60/892 : Active valves, i.e. actuated by an external force
• CPC Class Codes: A61M 60/894 : Passive valves, i.e. valves actuated by the blood
• CPC Class Codes: F04B 13/02 : of two or more fluids at the same time
• CPC Class Codes: F04B 23/06 : the pumps being all of reciprocating positive-displacement type
• CPC Class Codes: F04B 41/06 : Combinations of two or more pumps
• CPC Class Codes: F04B 43/00 : Machines, pumps, or pumping installations having flexible working members pumps or pumping installations specially adapted for elastic fluids F04B45/00
• CPC Class Codes: F04B 43/026 : each plate-like pumping flexible member working in its own pumping chamber
• CPC Class Codes: F04B 43/06 : Pumps having fluid drive
• CPC Class Codes: F04B 43/0736 : with two or more pumping chambers in parallel
• CPC Class Codes: F04B 45/02 : having bellows
• CPC Class Codes: F04B 45/0536 : the actuating fluid being controlled by one or more valves
• CPC Class Codes: F04B 49/02 : Stopping, starting, unloading or idling control
• CPC Class Codes: F04B 49/22 : by means of valves F04B49/03 takes precedence
• CPC Class Codes: F04B 53/06 : Venting
• CPC Class Codes: F04B 53/10 : Valves; Arrangement of valves
• CPC Class Codes: F04B 53/16 : Casings; Cylinders; Cylinder liners or heads; Fluid connections
• CPC Class Codes: F04B 7/02 : the valving being fluid-actuated
• CPC Class Codes: F04B 9/109 : having plural pumping chambers
• CPC Class Codes: F17D 3/00 : Arrangements for supervising or controlling working operations
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
• CPC Class Codes: Y10T 137/0324 : With control of flow by a condition or characteristic of a fluid
• CPC Class Codes: Y10T 137/0379 : By fluid pressure
• CPC Class Codes: Y10T 137/2521 : Flow comparison or differential response
• CPC Class Codes: Y10T 137/85978 : With pump
• CPC Class Codes: Y10T 137/86139 : Serial

Abstract

A pump cassette is disclosed. The pump cassette includes housing. The housing includes at least one fluid inlet line and at least one fluid outlet line. Also, the cassette includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps at least one fluid from the fluid inlet line to at least one of the fluid outlet line. Also, the cassette includes at least one mixing chamber within the housing. The mixing chamber is fluidly connected to the fluid outlet line.

Claims

1. A pump cassette comprising:

a housing;

a first reciprocating membrane pump in the housing having a first pump inlet and a first pump outlet, the first pump inlet in valved fluid communication with a first fluid port in the housing;

a second reciprocating membrane pump in the housing having a second pump inlet connected to a second fluid port in the housing and a second pump outlet in valved fluid communication with the first pump inlet;

a third reciprocating membrane pump in the housing having a third pump inlet connected to a third fluid port in the housing and a third pump outlet in valved fluid communication with the first pump outlet;

a fourth reciprocating membrane pump in the housing having a fourth pump inlet in valved fluid communication with the first fluid port in the housing, and a fourth pump outlet in valved fluid communication with a fifth fluid port in the housing;

a mixing chamber in the housing having an inlet in valved fluid communication with the first pump outlet and an outlet in valved fluid communication with a fourth fluid port in the housing;

a first conductivity sensing flow path arranged to connect the first pump outlet with a first conductivity sensor apparatus; and

a second conductivity sensing flow path arranged to connect the outlet of the mixing chamber with a second conductivity sensor apparatus;

wherein

the valved fluid communication comprises membrane-based valves, each valve having a flexible membrane, one side of which is configured and positioned to interrupt fluid flow through the valve upon application of pressure to an opposing side of the membrane.

2. The pump cassette of claim 1, the first conductivity sensing flow path, first conductivity sensing apparatus, second conductivity sensing flow path, and second conductivity sensing apparatus are contained within the housing.

3. A pump cassette comprising:

a housing;

a first reciprocating membrane pump in the housing having a first pump inlet and a first pump outlet, the first pump inlet in valved fluid communication with a first fluid port in the housing;

a second reciprocating membrane pump in the housing having a second pump inlet connected to a second fluid port in the housing and a second pump outlet in valved fluid communication with the first pump inlet;

a third reciprocating membrane pump in the housing having a third pump inlet connected to a third fluid port in the housing and a third pump outlet in valved fluid communication with the first pump outlet;

a mixing chamber in the housing having an inlet in valved fluid communication with the first pump outlet and an outlet in valved fluid communication with a fourth fluid port in the housing;

a first conductivity sensing flow path arranged to connect the first pump outlet with a first conductivity sensor apparatus configured to measure a conductivity of a fluid contained in the first conductivity sensing flow path; and

a second conductivity sensing flow path arranged to connect the outlet of the mixing chamber with a second conductivity sensor apparatus configured to measure a conductivity of a fluid contained in the first conductivity sensing flow path.

4. The pumping cassette of claim 3, wherein the housing comprises a stacked arrangement of a top plate, a bottom plate, and a midplate positioned between the top plate and the bottom plate.

5. The pump cassette of claim 3, wherein the first reciprocating membrane pump comprises a fluid-pumping chamber having a curved rigid wall separated from an actuation chamber by a flexible membrane, and wherein the actuation chamber comprises a port for delivering pressure to the flexible membrane to effect fluid pumping.

6. The pump cassette of claim 3, wherein the valved fluid communication comprises membrane-based valves, each valve having a flexible membrane, one side of which is configured and positioned to interrupt fluid flow through the valve upon application of pressure to an opposing side of the flexible membrane.

7. The pump cassette of claim 3, wherein each of the first and third reciprocating membrane pumps has a maximum pumping volume that is smaller than a maximum pumping volume of the second reciprocating membrane pump.

8. The pump cassette of claim 3, further comprising a fourth pump in the housing having a fourth pump inlet in valved fluid communication with the third fluid port in the housing, and a fourth pump outlet in valved fluid communication with a fifth fluid port in the housing.

9. The pump cassette of claim 3, wherein a flow path within the housing connecting the first pump outlet with the inlet of the mixing chamber comprises the first conductivity sensor apparatus, and the flow path within the housing connecting the outlet of the mixing chamber with the fourth fluid port in the housing comprises the second conductivity sensor apparatus.

10. The pump cassette of claim 3, wherein the valved fluid communication comprises membrane-based valves, each valve having a flexible membrane, one side of which is configured and positioned to interrupt fluid flow through the valve upon application of pressure to an opposing side of the membrane.

11. The pump cassette of claim 3, wherein the first conductivity sensing flow path, first conductivity sensing apparatus, second conductivity sensing flow path, and second conductivity sensing apparatus are contained within the housing.