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Modalities for the treatment of degenerative diseases of the retina

  • US 9,650,607 B2
  • Filed: 04/08/2013
  • Issued: 05/16/2017
  • Est. Priority Date: 01/23/2004
  • Status: Active Grant
First Claim
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1. A method for treating a retinal disease or condition in a human subject comprisingtransplanting, into the eye of the human subject, human RPE cells obtained by in vitro differentiation of human pluripotent cells that express Oct-4, alkaline phosphatase, SSEA-3, SSEA-4, TRA-I-60, and TRA-I-8I, wherein said RPE cells are disposed on a substrate or matrix, and have a normal karyotype, thereby treating the disease or condition as determined by functional testing.

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