System and method for electrical pulse charge compensation for implantable medical device capacitance loading effects

• US 9,656,084 B2
• Filed: 04/21/2015
• Issued: 05/23/2017
• Est. Priority Date: 04/25/2014
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: McDonald, Matthew Lee, Lamont, Robert Graham, Bocek, Joseph M., Stouffer, Thomas W.
• Primary Examiner(s): Wehrheim, Lindsey G
• Application Number:
  US14/692,582
• Publication Number:
  US 20150306399A1
• Time in Patent Office: 763 Days
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/086 Magnetic resonance imaging [MRI] compatible leads
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components
• CPC Class Codes: A61N 1/36142 for improving safety
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/36178 Burst or pulse train parameters
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

A neurostimulation device and system are provided. At least one neurostimulation lead having a plurality of electrodes is configured for being implanted within tissue of a patient. A shunt capacitance is coupled to one of the electrodes. Time-varying electrical current is delivered to at least one of the electrodes, wherein the shunt capacitance would, without compensation, absorb charge from or inject charge into the tissue in response to time-varying changes in the delivered electrical current, thereby causing an uncompensated electrical waveform to be delivered to the tissue adjacent the one electrode, The absorbed or injected charge is at least partially compensated for, thereby causing a compensated electrical waveform to be delivered to the tissue adjacent the one electrode.

Claims

1. A neurostimulation device, comprising:

a plurality of electrical terminals configured for being respectively coupled to a plurality of stimulation electrodes implanted within tissue of a patient;

stimulation output circuitry configured for delivering time-varying electrical current to at least one of the stimulation electrodes via at least one of the electrical terminals to stimulate the tissue of the patient, the stimulation output circuitry including a shunt capacitance coupled to the at least one of the stimulation electrodes via the at least one of the electrical terminals that would, without compensation, absorb charge from or inject charge into the tissue in response to time-varying changes in the delivered time-varying electrical current, thereby causing an uncompensated electrical waveform to be delivered to the tissue adjacent the at least one of the stimulation electrodes, wherein the uncompensated electrical waveform deviates from a desired electrical waveform; and

a controller configured for directing the stimulation output circuitry to at least partially compensate for the absorbed or injected charge, thereby causing a compensated electrical waveform to be delivered to the tissue adjacent the at least one of the stimulation electrodes, wherein the compensated electrical waveform matches the desired electrical waveform more closely than the uncompensated electrical waveform matches the desired electrical waveform.

2. The neurostimulation device of claim 1, wherein a characteristic between the uncompensated electrical waveform and the desired electrical waveform has a first error value, and the same characteristic between the compensated electrical waveform and the desired electrical waveform has a second error value less than the first error value.

3. The neurostimulation device of claim 2, wherein the characteristic is a total electrical charge over a period of time.

4. The neurostimulation device of claim 2, wherein the characteristic is a magnitude of an electrical current in a period of time.

5. The neurostimulation device of claim 4, wherein the electrical current is an average electrical current over the period of time.

6. The neurostimulation device of claim 2, wherein the characteristic is a waveform shape.

7. The neurostimulation device of claim 1, wherein the delivered time-varying electrical current comprises pulsed electrical energy having an electrical pulse having a rising edge and a falling edge, wherein the shunt capacitance would, without compensation, absorb charge from the tissue in response to a rising edge of the electrical pulse, and inject charge into the tissue in response to a falling edge of the electrical pulse.

8. The neurostimulation device of claim 1, wherein the controller is configured for directing the stimulation output circuitry to at least partially compensate for the absorbed or injected charge by actively injecting charge into the shunt capacitance when the shunt capacitance would, without compensation, remove charge from the tissue, and/or actively removing charge from the shunt capacitance when the shunt capacitance would, without compensation, inject charge into the tissue.

9. The neurostimulation device of claim 1, wherein the stimulation output circuitry comprises an electrical source configured for being coupled to the at least one of the stimulation electrodes via the at least one of the electrical terminals, and wherein the controller is configured for directing the electrical source to at least partially compensate for the absorbed or injected charge by generating an electrical current.

10. The neurostimulation device of claim 9, wherein the electrical source has an arbitrary pulse shaping capability that is configured to be controlled by the controller.

11. The neurostimulation device of claim 9, further comprising a processor configured for computing a value of the electrical current generated by the electrical source based on a differential equation that is a function of the shunt capacitance and a desired electrical current value.

12. The neurostimulation device of claim 9, further comprising:

a sensing device configured for measuring a change in a voltage at the at least one of the stimulation electrodes during the delivery of the time-varying electrical current; and

a processor configured for computing a magnitude and a polarity of electrical current flowing through the tissue adjacent the at least one of the stimulation electrodes based on a measured voltage change, computing a magnitude and a polarity of a compensating electrical current based on the computed magnitude and polarity of the electrical current flowing through the tissue adjacent the at least one of the stimulation electrodes and a desired electrical current value, and adding a function of the magnitude and polarity of the compensating electrical current to the desired electrical current value to obtain a magnitude and polarity of the electrical current that the controller directs the electrical source to generate.

13. The neurostimulation device of claim 12, wherein the function is one of a gain, a differentiation of the compensating electrical current over time multiplied by a gain, or an integration of the compensating electrical current over time multiplied by a gain.

14. A neurostimulation system comprising:

the neurostimulation device of claim 1;

at least one neurostimulation lead having the plurality of stimulation electrodes configured for being implanted within the tissue of the patient; and

the shunt capacitance coupled to the at least one of the stimulation electrodes.

15. The neurostimulation system of claim 14, wherein a characteristic between the uncompensated electrical waveform and the desired electrical waveform has a first error value, and the same characteristic between the compensated electrical waveform and the desired electrical waveform has a second error value less than the first error value.

16. The neurostimulation system of claim 15, wherein the characteristic is a total electrical charge over a period of time.

17. The neurostimulation system of claim 15, wherein the characteristic is a magnitude of an electrical current in a period of time.

18. The neurostimulation system of claim 17, wherein the electrical current is an average electrical current over the period of time.

19. The neurostimulation system of claim 15, wherein the characteristic is a waveform shape.

20. The neurostimulation system of claim 14, wherein the delivered time-varying electrical stimulation current comprises pulsed electrical energy having an electrical pulse having a rising edge and a falling edge, wherein the shunt capacitance would, without compensation, absorb charge from the tissue in response to a rising edge of the electrical pulse, and inject charge into the tissue in response to a falling edge of the electrical pulse.