Guanidine-functionalized particles and methods of making and using
First Claim
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1. A method of separating a target biological species from a fluid, comprising:
- contacting the fluid with a guanidine-functionalized particle;
allowing the target biological species to non-specifically bind with a guanidine group of the guanidine-functionalized particle wherein the guanidine group is of the formula NH—
C(NH)—
NH2 and wherein the guanidine group is covalently attached to the particle;
and,separating the fluid and the guanidine-functionalized particle with the target biological species non-specifically bound thereto, from each other.
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Abstract
Guanidine-functionalized particles and methods of making and using such particles.
22 Citations
15 Claims
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1. A method of separating a target biological species from a fluid, comprising:
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contacting the fluid with a guanidine-functionalized particle; allowing the target biological species to non-specifically bind with a guanidine group of the guanidine-functionalized particle wherein the guanidine group is of the formula NH—
C(NH)—
NH2 and wherein the guanidine group is covalently attached to the particle;and, separating the fluid and the guanidine-functionalized particle with the target biological species non-specifically bound thereto, from each other. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification