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Guanidine-functionalized particles and methods of making and using

  • US 9,657,038 B2
  • Filed: 11/20/2013
  • Issued: 05/23/2017
  • Est. Priority Date: 12/04/2012
  • Status: Active Grant
First Claim
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1. A method of separating a target biological species from a fluid, comprising:

  • contacting the fluid with a guanidine-functionalized particle;

    allowing the target biological species to non-specifically bind with a guanidine group of the guanidine-functionalized particle wherein the guanidine group is of the formula NH—

    C(NH)—

    NH2 and wherein the guanidine group is covalently attached to the particle;

    and,separating the fluid and the guanidine-functionalized particle with the target biological species non-specifically bound thereto, from each other.

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