Biomarker fusion system and method
First Claim
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1. An apparatus comprising:
- (a) a ERP testing system, wherein the ERP testing system is configured to administer an ERP test;
(b) a computer in communication with the ERP testing system, wherein the computer is configured to access a database of biomarkers, wherein the computer is configured to select at least one class set definition and at least one feature set definition, wherein the at least one class set definition includes a class set based on a variable present in the database of biomarkers, wherein the feature set definition comprises a biomarker based on additional biomarker criteria, wherein the computer is configured to form at least one training set definition from the at least one class set definition and the at least one feature set definition;
wherein the computer is further configured to automatically render an original diagnosis by fusing biomarker data using the training set definition, wherein at least some of the fused biomarker data is acquired through the ERP testing system.
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Abstract
An apparatus comprises an ERP testing system that is configured to administer an ERP test. The apparatus further comprises a computer in communication with the ERP testing system. The computer is operable to access a database of biomarkers. The computer is further operable to define at least one class set relating to biomarkers and at least one feature set relating to biomarkers. The computer is further operable to classify a test subject into at least one of the defined class sets based on information in the feature set relating to biomarkers of the test subject. The biomarker processing may be carried out in association with or completely independent of ERP testing.
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Citations
19 Claims
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1. An apparatus comprising:
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(a) a ERP testing system, wherein the ERP testing system is configured to administer an ERP test; (b) a computer in communication with the ERP testing system, wherein the computer is configured to access a database of biomarkers, wherein the computer is configured to select at least one class set definition and at least one feature set definition, wherein the at least one class set definition includes a class set based on a variable present in the database of biomarkers, wherein the feature set definition comprises a biomarker based on additional biomarker criteria, wherein the computer is configured to form at least one training set definition from the at least one class set definition and the at least one feature set definition; wherein the computer is further configured to automatically render an original diagnosis by fusing biomarker data using the training set definition, wherein at least some of the fused biomarker data is acquired through the ERP testing system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A system for constructing a meta-model, the system comprising:
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(a) a computer configured to output a selection dialog for defining a class set, wherein the computer is further configured to output a second selection dialog for defining a feature set, wherein the computer is configured to combine the class set definition and the feature set definition into a training set definition, wherein the class set definition comprises a class set based on a first selected biomarker, wherein the feature set definition comprises a feature set based on a second biomarker, wherein the first biomarker and the second biomarker have no known relationship, wherein the training set definition is transmitted to an expert classifier module; and (b) a storage device configured to store a database of biomarker information, wherein the computer and the storage device are in communication with each other, wherein the computer is operable to retrieve biomarker information from the storage device in association with the expert classifier module; wherein the computer is further configured to execute the expert classifier module to thereby automatically generate an original diagnosis of a patient exhibiting a biomarker used in at least one of the class set definition or the feature set definition. - View Dependent Claims (16, 17, 18, 19)
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Specification