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Portable raman diagnostic system

  • US 9,662,047 B2
  • Filed: 06/23/2011
  • Issued: 05/30/2017
  • Est. Priority Date: 08/05/2010
  • Status: Active Grant
First Claim
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1. A method for measuring glucose concentration in a patient comprising:

  • illuminating a region of tissue with light including a plurality of sequential illumination wavelengths;

    detecting Raman shifted light from the tissue with a detector in response to the plurality of sequential illumination wavelengths of light;

    determining, with a data processor, a subset of the sequential illumination wavelengths using error minimization to define a plurality of separated spectral illumination bands, each spectral illumination band including a plurality of different illumination wavelengths, the determining step including processing the detected Raman shifted light to determine the illumination wavelengths of the plurality of separated spectral illumination bands;

    subsequently, illuminating a region of tissue in the patient, the region of tissue having a glucose concentration to be measured, with illuminating light having the plurality of different illumination wavelengths within each of the plurality of separated spectral illumination bands;

    detecting light from the tissue with the detector in response to the plurality of separated spectral illumination bands of light, the detector generating Raman spectral data; and

    analyzing the Raman spectral data with the data processor to determine a concentration of glucose in the region of tissue in the patient.

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