Multi-element coupler for generation of electromagnetic energy

• US 9,662,507 B2
• Filed: 06/29/2016
• Issued: 05/30/2017
• Est. Priority Date: 09/16/2013
• Status: Active Grant

• Current Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Original Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Inventors: Poon, Ada Shuk Yan, Yeh, Alexander Jueshyan, Tanabe, Yuji, Ho, John, Kim, Sanghoek
• Primary Examiner(s): Gedeon, Brian T
• Application Number:
  US15/196,874
• Publication Number:
  US 20160303386A1
• Time in Patent Office: 335 Days
• Field of Search: None
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/0013 Medical image data A61B1/00011, A61B6/56, A61B8/56 take precedence
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61H 1/008 Apparatus for applying pressure or blows almost perpendicular to the body or limb axis, e.g. chiropractic devices for repositioning vertebrae, correcting deformation
• CPC Class Codes: A61H 2201/1207 with electric or magnetic drive
• CPC Class Codes: A61H 23/004 With mechanical drive, e.g. spring mechanism or vibrating unit being hit for starting vibration and then applied to the body of a patient
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0551 : Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/056 : Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/3601 : of respiratory organs
• CPC Class Codes: A61N 1/3605 : Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36125 : Details of circuitry or electric components
• CPC Class Codes: A61N 1/36139 : with automatic adjustment
• CPC Class Codes: A61N 1/3629 : in combination with non-electric therapy
• CPC Class Codes: A61N 1/365 : controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/37211 : Means for communicating with stimulators
• CPC Class Codes: A61N 1/37229 : Shape or location of the implanted or external antenna
• CPC Class Codes: A61N 1/3756 : Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3787 : from an external energy source
• CPC Class Codes: A61N 5/0601 : Apparatus for use inside the body
• CPC Class Codes: A61N 7/00 : Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092
• CPC Class Codes: H01Q 1/273 : Adaptation for carrying or wearing by persons or animals
• CPC Class Codes: H01Q 9/0407 : Substantially flat resonant element parallel to ground plane, e.g. patch antenna dipole H01Q9/285; monopole H01Q9/40
• CPC Class Codes: H02J 2310/23 : The load being a medical device, a medical implant, or a life supporting device
• CPC Class Codes: H02J 50/005 : Mechanical details of housing or structure aiming to accommodate the power transfer means, e.g. mechanical integration of coils, antennas or transducers into emitting or receiving devices
• CPC Class Codes: H02J 50/10 : using inductive coupling
• CPC Class Codes: H02J 50/20 : using microwaves or radio frequency waves
• CPC Class Codes: H02J 50/23 : characterised by the type of transmitting antennas, e.g. directional array antennas or Yagi antennas
• CPC Class Codes: H02J 7/00034 : Charger exchanging data with an electronic device, i.e. telephone, whose internal battery is under charge

Abstract

Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient'"'"'s tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.

Claims

1. An apparatus configured to transfer wireless power through tissue, comprising:

a substrate;

multiple sub-wavelength structures disposed on the substrate;

multiple radio-frequency ports respectively coupled to the multiple sub-wavelength structures;

a voltage or current source coupled to the multiple radio-frequency ports; and

a controller configured to manage excitation of the radio-frequency ports and sub-wavelength structures with the voltage or current source to manipulate evanescent fields outside of tissue to generate propagating fields inside the tissue and thereby generate a spatially focused field in the tissue.

2. The apparatus of claim 1, wherein the voltage or current source is configured to provide respective excitation signals to the sub-wavelength structures via the radio-frequency ports.

3. The apparatus of claim 2, wherein the controller is configured to update an amplitude and/or phase characteristic of at least one of the excitation signals to adjust a focus of the field in the tissue.

4. The apparatus of claim 1, wherein the multiple sub-wavelength structures include at least one sub-wavelength structure having one of a patch structure, a slot structure, a cross slot structure, a circular slot structure, and a half slot structure.

5. The apparatus of claim 1, wherein the multiple sub-wavelength structures include multiple circular slot structures.

6. The apparatus of claim 1, wherein the controller is configured to initiate a patient electrostimulation therapy by exciting the sub-wavelength structures to generate a propagating field inside the tissue such that a portion of the propagating field reaches an implanted receiver device that is responsive to the field.

7. The apparatus of claim 1, wherein the substrate is a flexible substrate configured to conform to a patient body surface.

8. The apparatus of claim 1, further comprising a receiver circuit configured to receive information about a quantity of power received by an implanted device from the apparatus.

9. The apparatus of claim 8, wherein the controller is configured to manage the excitation of the sub-wavelength structures based on the received power signal information.

10. The apparatus of claim 9, wherein the controller is configured to update an amplitude or phase characteristic of an excitation signal provided to at least one of the radio-frequency ports and sub-wavelength structures, the updated amplitude or phase characteristic selected to change a focal point of the field in the tissue.

11. The apparatus of claim 1, further comprising a receiver circuit configured to receive data communications from an implanted device using pulsed RF modulation.

12. An apparatus configured to transfer wireless power through tissue, comprising:

multiple sub-wavelength structures provided externally to a patient body and configured to generate, in response to respective excitation signals corresponding to each of the multiple sub-wavelength structures, a spatially adaptable propagating electromagnetic field inside the patient'"'"'s body;

multiple independent feed ports configured to excite respective ones of the multiple sub-wavelength structures to generate the spatially adaptable propagating electromagnetic field; and

a controller configured to update a focus and/or an output power of the spatially adaptable propagating electromagnetic field by exciting the sub-wavelength structures using updated excitation signals.

13. The apparatus of claim 12, wherein the multiple sub-wavelength structures are further configured to generate a steerable field inside the patient'"'"'s body based on adjustable characteristics of the excitation signals.

14. The apparatus of claim 12, wherein the controller is configured to excite the sub-wavelength structures using excitation signals between about 300 MHz and 3000 MHz.

15. The apparatus of claim 12, wherein the controller is configured to update the focus and/or output power of the field in response to information received from an implanted electrostimulation device about a quantity of power received from the apparatus.

16. The apparatus of claim 12, wherein the controller is configured to update the focus of the propagating electromagnetic field to concentrate the field in the direction of a particular one of multiple implanted receiver devices.

17. An apparatus configured to transfer wireless power through tissue, comprising:

multiple sub-wavelength structures;

a signal generator configured to provide respective excitation signals to each of the multiple sub-wavelength structures; and

a controller configured to use the signal generator to provide the excitation signals to the multiple sub-wavelength structures to generate and transmit a wireless power signal by manipulating evanescent fields outside of a patient'"'"'s body and thereby control electromagnetic waves propagating inside the patient'"'"'s body;

wherein the controller is configured to select different excitation signal characteristics for at least two of the respective excitation signals to focus the electromagnetic waves propagating inside the patient'"'"'s body toward a target receiver device implanted in the patient.

18. The apparatus of claim 17, wherein the multiple sub-wavelength structures include two or more of a patch structure, a slot structure, a cross slot structure, a circular slot structure, and a half slot structure.

19. The apparatus of claim 17, further comprising a receiver circuit configured to receive information from the target receiver device implanted in the patient, the information including an indication of a quantity of power wirelessly received from the apparatus.

20. An apparatus configured to transfer wireless power through tissue, comprising:

a substrate;

multiple sub-wavelength structures disposed on the substrate;

multiple radio-frequency ports respectively coupled to the multiple sub-wavelength structures;

a voltage or current source configured to provide respective excitation signals to the sub-wavelength structures via the radio-frequency ports; and

a controller configured to manage excitation of the sub-wavelength structures with the voltage or current source to manipulate evanescent fields outside of tissue to generate propagating fields inside the tissue and thereby generate a spatially focused field in the tissue.

21. The apparatus of claim 20, wherein the controller is configured to update an amplitude and/or phase characteristic of at least one of the excitation signals to adjust a focus of the field in the tissue.

22. The apparatus of claim 20, wherein the controller is configured to update an amplitude and/or phase characteristic of at least one of the excitation signals to adjust a focus of the field in the tissue.

23. The apparatus of claim 20, wherein the multiple sub-wavelength structures include one or more of a patch structure, a slot structure, a cross slot structure, a circular slot structure, and a half slot structure.

24. The apparatus of claim 20, wherein the controller is configured to initiate a patient electrostimulation therapy by exciting the multiple sub-wavelength structures to generate a propagating field inside the tissue such that a portion of the propagating field reaches an implanted receiver device that is responsive to the field.

25. The apparatus of claim 20, further comprising a receiver circuit configured to receive information about a quantity of power received by an implanted device from the apparatus.

26. An apparatus configured to transfer wireless power through tissue, comprising:

a substrate;

at least one sub-wavelength structure disposed on the substrate, wherein the at least one sub-wavelength structure includes one of a patch structure, a slot structure, a cross slot structure, a circular slot structure, and a half slot structure;

at least one radio-frequency port coupled to the at least one sub-wavelength structure,

a voltage or current source coupled to the at least one radio-frequency port; and

a controller configured to manage excitation of the at least one radio-frequency port and sub-wavelength structure with the voltage or current source to manipulate evanescent fields outside of tissue to generate propagating fields inside the tissue and thereby generate a spatially focused field in the tissue.

27. The apparatus of claim 26, further comprising multiple sub-wavelength structures and multiple radio-frequency ports, wherein each sub-wavelength structure is coupled to a different respective radio-frequency port.

28. The apparatus of claim 27, wherein the voltage or current source is configured to provide respective excitation signals to the sub-wavelength structures via the radio-frequency ports.

29. The apparatus of claim 28, wherein the controller is configured to update an amplitude and/or phase characteristic of at least one of the excitation signals to adjust a focus of the field in the tissue.

30. The apparatus of claim 26, wherein the at least one sub-wavelength structure includes one of a patch structure, a slot structure, a cross slot structure, a circular slot structure, and a half slot structure.

31. The apparatus of claim 26, wherein the controller is configured to initiate a patient electrostimulation therapy by exciting the at least one-sub-wavelength structure to generate a propagating field inside the tissue such that a portion of the propagating field reaches an implanted receiver device that is responsive to the field.

32. The apparatus of claim 26, wherein the substrate is a flexible substrate configured to conform to a patient body surface.

33. The apparatus of claim 26, further comprising a receiver circuit configured to receive information about a quantity of power received by an implanted device from the apparatus.

34. An apparatus configured to transfer wireless power through tissue, comprising:

a substrate;

multiple sub-wavelength structures disposed on the substrate, wherein the multiple sub-wavelength structures include circular slot structures;

multiple radio-frequency ports respectively coupled to the multiple sub-wavelength structures;

a voltage or current source coupled to the multiple radio-frequency ports; and

a controller configured to manage excitation of the multiple radio-frequency ports and sub-wavelength structures with the voltage or current source to manipulate evanescent fields outside of tissue to generate propagating fields inside the tissue and thereby generate a spatially focused field in the tissue.

35. The apparatus of claim 34, wherein the voltage or current source is configured to provide respective excitation signals to the sub-wavelength structures via the radio-frequency ports.

36. The apparatus of claim 34, wherein the controller is configured to update an amplitude and/or phase characteristic of at least one of the excitation signals to adjust a focus of the field in the tissue.

37. The apparatus of claim 34, wherein the controller is configured to initiate a patient electrostimulation therapy by exciting the wavelength structures to generate a propagating field inside the tissue such that a portion of the propagating field reaches an implanted receiver device that is responsive to the field.

38. The apparatus of claim 34, wherein the substrate is a flexible substrate configured to conform to a patient body surface.

39. The apparatus of claim 34, further comprising a receiver circuit configured to receive information about a quantity of power received by an implanted device from the apparatus.

40. An apparatus configured to transfer wireless power through tissue, comprising:

a flexible substrate configured to conform to a patient body surface;

at least one sub-wavelength structure disposed on the flexible substrate;

at least one radio-frequency port coupled to the at least one sub-wavelength structure;

a voltage or current source coupled to the at least one radio-frequency port; and

a controller configured to manage excitation of the at least one radio-frequency port and sub-wavelength structure with the voltage or current source to manipulate evanescent fields outside of tissue to generate propagating fields inside the tissue and thereby generate a spatially focused field in the tissue.

41. The apparatus of claim 40, further comprising multiple sub-wavelength structures and multiple radio-frequency ports, wherein each sub-wavelength structure is coupled to a different respective radio-frequency port.

42. The apparatus of claim 41, wherein the voltage or current source is configured to provide respective excitation signals to the sub-wavelength structures via the radio-frequency ports.

43. The apparatus of claim 42, wherein the controller is configured to update an amplitude and/or phase characteristic of at least one of the excitation signals to adjust a focus of the field in the tissue.

44. The apparatus of claim 40, wherein the at least one sub-wavelength structure includes one of a patch structure, a slot structure, a cross slot structure, a circular slot structure, and a half slot structure.

45. The apparatus of claim 40, wherein the controller is configured to initiate a patient electrostimulation therapy by exciting the at least one-sub-wavelength structure to generate a propagating field inside the tissue such that a portion of the propagating field reaches an implanted receiver device that is responsive to the field.

46. The apparatus of claim 40, further comprising a receiver circuit configured to receive information about a quantity of power received by an implanted device from the apparatus.

47. An apparatus configured to transfer wireless power through tissue, comprising:

a substrate;

at least one sub-wavelength structure disposed on the substrate;

at least one radio-frequency port coupled to the at least one sub-wavelength structure;

a voltage or current source coupled to the at least one radio-frequency port; and

a controller configured to manage excitation of the at least one radio-frequency port and sub-wavelength structure with the voltage or current source to manipulate evanescent fields outside of tissue to generate propagating fields inside the tissue and thereby generate a spatially focused field in the tissue; and

a receiver circuit configured to receive information about a quantity of power received by an implanted device from the apparatus, wherein the controller is configured to manage the excitation of the at least one radio-frequency port and sub-wavelength structure based on the received information about the quantity of power.

48. The apparatus of claim 47, further comprising multiple sub-wavelength structures and multiple radio-frequency ports, wherein each sub-wavelength structure is coupled to a different respective radio-frequency port.

49. The apparatus of claim 48, wherein the voltage or current source is configured to provide respective excitation signals to the sub-wavelength structures via the radio-frequency ports.

50. The apparatus of claim 49, wherein the controller is configured to update an amplitude and/or phase characteristic of at least one of the excitation signals to adjust a focus of the field in the tissue.

51. The apparatus of claim 47, wherein the at least one sub-wavelength structure includes one of a patch structure, a slot structure, a cross slot structure, a circular slot structure, and a half slot structure.

52. The apparatus of claim 47, wherein the controller is configured to initiate a patient electrostimulation therapy by exciting the at least one-sub-wavelength structure to generate a propagating field inside the tissue such that a portion of the propagating field reaches an implanted receiver device that is responsive to the field.

53. The apparatus of claim 47, wherein the substrate is a flexible substrate configured to conform to a patient body surface.

54. The apparatus of claim 47, further comprising a receiver circuit configured to receive information about a quantity of power received by an implanted device from the apparatus.