Analyte sensor

• US 9,668,677 B2
• Filed: 10/26/2015
• Issued: 06/06/2017
• Est. Priority Date: 07/13/2004
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark C., Saint, Sean, Petisce, James R., Woo, Kum Ming, Nolting, John
• Primary Examiner(s): Natnithithadha, Navin
• Application Number:
  US14/923,350
• Publication Number:
  US 20160045145A1
• Time in Patent Office: 589 Days
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 2017/3492 against the outside of the body
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/045 with a separable interface unit, e.g. for communication
• CPC Class Codes: A61B 2562/18 Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/14 Devices for taking samples of blood hypodermic syringes A61M5/00; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood measuring of blood pressure A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/1411 by percutaneous method, e.g. by lancet
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/14735 comprising an immobilised reagent
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/14865 : invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 : Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/150022 : for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/6801 : specially adapted to be attached to or worn on the body surface
• CPC Class Codes: A61B 5/6833 : Adhesive patches
• CPC Class Codes: A61B 5/68335 : including release sheets or liners
• CPC Class Codes: A61B 5/6848 : Needles
• CPC Class Codes: A61B 5/6849 : in combination with a needle set
• CPC Class Codes: A61B 5/72 : Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61M 2005/1585 : Needle inserters
• CPC Class Codes: A61M 5/14244 : adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Claims

1. An applicator system configured to insert a transcutaneous analyte sensor into a host, the applicator system comprising:

a housing configured for placement against a skin of the host;

a sensor configured for transcutaneous placement through the skin of a host;

a needle configured to aid the sensor for placement through the skin; and

an applicator comprising applicator components configured to insert the needle and the sensor into the host, wherein the applicator components are configured to rotatingly engage one another by a continuous torque which inserts the sensor and needle into the host the continuous torque configured to subsequently retract the needle from the host, wherein the sensor is inserted into the host to a predetermined depth.

2. The system of claim 1, further comprising sensor electronics configured to be releasably electrically connected to the sensor.

3. The system of claim 2, further comprising a sealing member configured to seal the electrical connection of the sensor with the sensor electronics from external moisture when the sensor electronics are releasably electrically connected to the sensor.

4. The system of claim 1, wherein the applicator is releasably connected to the housing.

5. The system of claim 4, wherein the releasable connection is automatic.

6. The system of claim 1, wherein the housing comprises a body and an adhesive configured for adhering the body to the skin of the host.

7. The system of claim 6, further comprising a vent hole located between the body and the adhesive.

8. The system of claim 6, wherein the body is flexible.

9. A method for inserting a transcutaneous analyte sensor into a host using an applicator, the method comprising:

placing the applicator against a skin of the host, the applicator including

a housing configured for placement against a skin of the host,

a sensor configured for transcutaneous placement through the skin of the host,

a needle configured to aid the sensor for placement through the skin, and

applicator components configured for inserting the sensor and needle into the skin of the host; and

applying a continuous torque to the applicator components, wherein the continuous torque causes the applicator components to rotatingly engage one another to insert the needle and the sensor into the host and subsequently retract the needle from the host.

10. The method of claim 9, wherein the applicator further comprises sensor electronics configured to be releasably electrically connected to the sensor.

11. The method of claim 10, wherein the applicator further comprises a sealing member configured to seal the electrical connection of the sensor with the sensor electronics from external moisture when the sensor electronics are releasably electrically connected to the sensor.

12. The method of claim 9, wherein the housing comprises a body and an adhesive configured for adhering the body to the skin of the host.

13. The method of claim 12, wherein the applicator further comprises a vent hole located between the body and the adhesive.

14. The method of claim 12, wherein the body is flexible.