Tracking brain deformation during neurosurgery

• US 9,668,710 B2
• Filed: 03/01/2012
• Issued: 06/06/2017
• Est. Priority Date: 03/18/2011
• Status: Active Grant

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Ruijters, Danil Simon Anna, Babic, Drazenko
• Primary Examiner(s): TSAI, TSUNG YIN
• Application Number:
  US14/005,620
• Publication Number:
  US 20140003698A1
• Time in Patent Office: 1,923 Days
• Field of Search: None
• CPC Class Codes: A61B 6/461 Displaying means of special interest
• CPC Class Codes: A61B 6/467 characterised by special input means
• CPC Class Codes: A61B 6/501 for diagnosis of the head, e.g. neuroimaging or craniography
• CPC Class Codes: A61B 6/5217 extracting a diagnostic or physiological parameter from medical diagnostic data
• CPC Class Codes: A61B 6/5235 combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
• CPC Class Codes: A61B 6/5247 combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/30016 Brain
• CPC Class Codes: G06T 2207/30101 Blood vessel; Artery; Vein; Vascular
• CPC Class Codes: G06T 7/33 using feature-based methods

Abstract

An imaging system for tracking brain deformation, a method for tracking brain deformation, a method of operating a device for tracking brain deformation are disclosed. A first 3D representation (112) of a cerebrovascular vessel structure of a region of interest of an object is provided (110), and (114) a second 3D representation (116) of the cerebrovascular vessel structure are used to determine brain deformation. At least a part of the first 3D representation is elastically three-dimensionally registered (118) with at least a part of the second 3D representation. A deformation field (122) of the cerebrovascular vessel structure is determined (120) based on the elastic registration. The determined vessel deformation is applied (124) to a brain structure representation to determine a deformation (126) of the cerebral structure.

Claims

1. A device for tracking brain deformation, the device comprising:

a processor; and

an image acquisition device that acquires and provides to the processor a first 3D representation of a cerebrovascular vessel structure of a region of interest of an object and a second 3D representation, which is based on X-ray image data, of the cerebrovascular vessel structure,

wherein the processor;

elastically three-dimensionally registers the first 3D representation with the second 3D representation,

determines, after executing the elastic registration, a deformation field indicating vessel deformation of the cerebrovascular vessel structure based on the elastic registration of the first 3D representation with the second 3D representation, and

applies the determined vessel deformation to a brain structure representation to determine a deformation of the brain structure.

2. The device according to claim 1, wherein the processor applies the determined deformation of the brain structure to planning data, for an intervention of the brain structure, to generate deformation adjusted planning data.

3. The device according to claim 1, wherein:

the processor extrapolates the determined vessel deformation to the brain structure representation;

the brain structure representation comprises a vessel structure and a lobe structure comprising a number of convolutions in which the vessels are arranged; and

the processor applies the deformation to the lobes only.

4. The device according to claim 1, wherein:

the image acquisition device acquires and provides to the processor a further 3D representation of a further cerebrovascular structure;

the further cerebrovascular structure is based on a morphological brain scan or a functional brain scan; and

the processor applies the determined vessel deformation to the further cerebrovascular structure.

5. The device according to claim 1, wherein:

the processor generates a deformation indicator from the deformation of the brain structure; and

the device further comprises;

a display that displays the deformation indicator to a user.

6. The device according to claim 2, wherein the processor provides the deformation adjusted planning data to an external navigation system.

7. An imaging system for tracking brain deformation, the system comprising:

the device according to claim 1, wherein

the image acquisition device is an X-ray image acquisition device that acquires the second 3D representation as 3D X-ray image data in a contactless manner.

8. The imaging system according to claim 7, wherein:

the X-ray image acquisition device is adapted to acquire the first and the second 3D representations with the same imaging modality; and

the X-ray image acquisition device generates the first and the second 3D representations with the same processing steps.

9. A method for tracking brain deformation, the method comprising:

a) acquiring, with an image acquisition device, a first 3D representation of a cerebrovascular vessel structure of a region of interest of an object;

b) acquiring, with the image acquisition device, a second 3D representation of the cerebrovascular vessel structure that is based on X-ray image data;

c) elastically three-dimensionally registering, with a processor, the first 3D representation with the second 3D representation;

d) determining, with the processor after executing the elastic registration specified by operation (c), a deformation field indicating vessel deformation of the cerebrovascular vessel structure based on the elastic registration of the first 3D representation with the second 3D representation; and

e) applying, with the processor, the determined vessel deformation to a brain structure representation to determine a deformation of the brain structure.

10. The method according to claim 9, further comprising:

acquiring, with the processor, planning data for an intervention of the brain structure; and

applying, with the processor and upon completing operation (e), the determined deformation of the brain structure to the planning data to generate deformation adjusted planning data.

11. A non-transitory computer readable medium comprising instructions executable by a processing device to cause an apparatus to perform the method of claim 9.