Methods of closing wounds

• US 9,669,131 B2
• Filed: 01/02/2014
• Issued: 06/06/2017
• Est. Priority Date: 12/16/1997
• Status: Expired due to Fees

• Current Assignee: St. Croix Surgical Systems, LLC
• Original Assignee: St. Croix Surgical Systems, LLC
• Inventors: Nowakowski, Karol L.
• Primary Examiner(s): Dornbusch, Dianne
• Application Number:
  US14/146,139
• Publication Number:
  US 20140193512A1
• Time in Patent Office: 1,251 Days
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00637 for sealing trocar wounds through abdominal wall
• CPC Class Codes: A61B 2017/00641 for closing fistulae, e.g. anorectal fistulae
• CPC Class Codes: A61B 2017/0065 the implement being an adhesive
• CPC Class Codes: A61L 24/0005 Ingredients of undetermined constitution or reaction products thereof
• CPC Class Codes: A61M 2025/0681 Systems with catheter and outer tubing, e.g. sheath, sleeve or guide tube
• CPC Class Codes: A61M 25/0662 Guide tubes

Abstract

Wound closure methods and apparatuses are provided which utilize blood fluid by activating the clotting cascade of the blood fluid outside the body within a substantially enclosed sterile container then introducing coagulated blood to the wound site to complete clotting. Methods and apparatuses for providing ways of inhibiting anticoagulants and slowing fibrin clot degradation are also disclosed. Kits for practicing the invention singularly or in combination with and/or associated with preferred procedures are also disclosed.

Claims

1. A method of percutaneously closing a puncture in the wall of an artery of a patient, comprising:

introducing a catheter percutaneously into the artery of the patient;

homogenously exposing the patient'"'"'s arterial whole blood to a porous matrix that is not of biological origin;

situating the exposed blood at a position proximate the puncture as the blood is clotting;

removing the catheter from the artery as the blood is clotting; and

holding the exposed blood at the position as the blood continues to clot;

thereby forming a hemostatic closure comprising the patient'"'"'s whole blood.

2. The method of claim 1, wherein the porous matrix comprises beads.

3. The method of claim 1, wherein the hemostatic closure comprises a cross-linked polymer.

4. The method of claim 3, wherein the cross-linked polymer comprises clotted whole blood.

5. The method of claim 3, further comprising transporting the cross-linked polymer from a position outside the patient'"'"'s body to a position proximate the puncture.

6. The method of claim 1, wherein the exposing occurs outside of the patient.

7. The method of claim 1, wherein the exposed blood, at the time of the situating, is actively clotting.