Automatic anode and cathode fractional control and location to selectively avoid dorsal root stimulation

• US 9,669,222 B2
• Filed: 04/12/2016
• Issued: 06/06/2017
• Est. Priority Date: 10/30/2013
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Ranu, Emarit A. S.
• Primary Examiner(s): Wieland, Robert N
• Application Number:
  US15/097,056
• Publication Number:
  US 20160220823A1
• Time in Patent Office: 420 Days
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

A therapeutic neurostimulation system configured for providing therapy to a patient. The neurostimulation system comprises a neurostimulation lead having an array of electrodes arranged along a longitudinal axis configured for being implanted along a spinal cord of a patient, a neurostimulation device configured for delivering electrical stimulation energy to active ones of the electrode array, and control/processing circuitry for instructing the neurostimulation device to configure an active electrode as a cathode, and two active electrodes longitudinally flanking and laterally offset from the cathode as anodes, selecting a ratio of stimulation amplitude values for the two anodes based on a known longitudinal location of the implanted neurostimulation lead relative to the spinal cord, and instructing the neurostimulation device to distribute the electrical stimulation energy between the two anodes in accordance with the selected stimulation amplitude value ratio.

Claims

1. A method of providing therapy to a patient using an array of electrodes arranged along a longitudinal axis of the spinal column of the patient, the method comprising:

determining a longitudinal location of the electrode array relative to the spinal cord;

configuring an electrode in the array of electrodes as a cathode, and two electrodes in the array of electrodes longitudinally flanking and laterally offset from the cathode as anodes;

selecting a ratio of stimulation amplitude values for the two anodes based on the determined longitudinal location of the electrode array relative to the spinal cord; and

delivering electrical stimulation energy to the active ones of the electrodes, such that the electrical stimulation energy is distributed between the two anodes in accordance with the selected stimulation amplitude value ratio.

2. The method of claim 1, wherein the longitudinal location of the electrode array relative to the spinal cord is automatically determined.

3. The method of claim 1, wherein the longitudinal location of the electrode array relative to the spinal cord is manually determined.

4. The method of claim 1, wherein a first ratio of stimulation amplitude values the two anodes is selected if the longitudinal location is in a cervical region of the spinal cord, and a second ratio of the stimulation amplitudes for the two anodes is selected if the longitudinal location is in a thoracic region of the spinal cord, wherein the first stimulation amplitude ratio is closer to unity than the second stimulation amplitude ratio.

5. The method of claim 4, further comprising determining the more rostral one of the two anodes and the more caudal one of the two anodes, wherein the stimulation amplitude value for the more rostral anode is greater than the stimulation amplitude value for the more caudal anode.

6. The method of claim 4, wherein the second stimulation amplitude ratio is at least two.

7. The method of claim 4, wherein the second stimulation amplitude ratio is at least four.

8. The method of claim 1, wherein the two anodes are immediately adjacent to the cathode.

9. The method of claim 1, wherein the stimulation amplitude values are electrical current values.

10. The method of claim 1, further comprising storing a look-up table containing a plurality of different stimulation amplitude ratios and associated neurostimulation lead locations, wherein the stimulation amplitude ratio is selected by matching the determined longitudinal location of the neurostimulation lead relative to the spinal cord with one of the neurostimulation lead locations stored in the look-up table and selecting the stimulation amplitude ratio associated with the matched neurostimulation lead location.

11. The method of claim 1, further comprising:

configuring two other active electrodes longitudinally flanking the cathode in a third one of the columns as anodes, wherein the first column is between the second and third columns;

selecting another ratio of stimulation amplitude values for the two other anodes based on the known longitudinal location of the implanted neurostimulation lead relative to the spinal cord, wherein the electrical stimulation energy is delivered to the active ones of the electrodes, such that the electrical stimulation energy is distributed between the two anodes in accordance with the other selected stimulation amplitude value ratio.

12. The method of claim 1, wherein the electrical stimulation energy is delivered to the active ones of the electrodes in a manner that decreases a dorsal column (DC)/dorsal root (DR) threshold ratio of the spinal cord.

13. The method of claim 1, wherein the patient suffers from chronic pain, and the delivery of the electrical stimulation energy alleviates the chronic pain.

14. The method of claim 1, wherein the electrode array is arranged in a plurality of columns along the longitudinal axis of the spinal column of the patient, the cathode is in a first one of the columns, and the two anodes are in a second one of the columns.

15. A method, comprising:

configuring an implanted electrode as a cathode, and two implanted electrodes longitudinally flanking and laterally offset from the cathode as anodes;

selecting a ratio of stimulation amplitude values for the two anodes based on a longitudinal location of the implanted electrodes relative to the spinal cord; and

delivering electrical stimulation energy to the active ones of the electrodes, such that the electrical stimulation energy is distributed between the two anodes in accordance with the selected stimulation amplitude value ratio.

16. The method of claim 15, further comprising automatically determining the longitudinal location of the implanted electrodes relative to the spinal cord, wherein selecting the ratio includes selecting the ratio based on the automatically-determined longitudinal location.

17. The method of claim 15, further comprising receiving a manually determined longitudinal location of the implanted electrodes relative to the spinal cord, wherein selecting the ratio includes selecting the ratio based on the manually-determined longitudinal location.

18. The method of claim 15, wherein selecting a ratio includes selecting a first ratio of stimulation amplitude values for the two anodes is selected when the longitudinal location is in a cervical region of the spinal cord or selecting a second ratio of the stimulation amplitudes for the two anodes is selected when the longitudinal location is in a thoracic region of the spinal cord, wherein the first stimulation amplitude ratio is closer to unity than the second stimulation amplitude ratio.

19. The method of claim 18, wherein the second stimulation amplitude ratio is at least two.

20. The method of claim 18, wherein the second stimulation amplitude ratio is at least four.