Telomerase activating compounds and methods of use thereof
First Claim
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1. A method of stimulating or increasing telomerase activity in an islet cell or in pancreatic tissue of a subject, said method comprising contacting said islet cell or pancreatic tissue of said subject with an effective amount of a compound represented by the structure of formula I:
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Abstract
The present invention is directed to use of a series of compounds and compositions comprising the same for activating telomerase and treating diseases, disorders and/or conditions related thereto.
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18 Claims
- 1. A method of stimulating or increasing telomerase activity in an islet cell or in pancreatic tissue of a subject, said method comprising contacting said islet cell or pancreatic tissue of said subject with an effective amount of a compound represented by the structure of formula I:
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17. A method of stimulating or increasing telomerase activity in an islet cell or in pancreatic tissue of a subject, said method comprising contacting said islet cell or pancreatic tissue of said subject, who has diabetes and is in need of increased telomerase activity, with an effective amount of a compound represented by the structure of formula I:
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18. A method of stimulating or increasing telomerase activity in an islet cell or in pancreatic tissue of a subject, said method comprising contacting said islet cell or pancreatic tissue of said subject, who is predisposed to diabetes and in need of increased telomerase activity, with an effective amount of a compound represented by the structure of formula I:
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