Anti-paravalvular leakage component for a transcatheter valve prosthesis
First Claim
1. A transcatheter valve prosthesis comprising:
- a tubular stent having a proximal end, a distal end and a longitudinal axis, the tubular stent having a compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve;
a prosthetic valve component disposed within and secured to the tubular stent; and
an anti-paravalvular leakage component coupled to and encircling an outer surface of the tubular stent, the anti-paravalvular leakage component including a plurality of self-expanding segments and an annular sealing element attached to the plurality of self-expanding segments, a first end and a second end of each self-expanding segment being attached directly to the outer surface of the tubular stent at first and second attachment points, respectively, the first and second attachment points being at axially spaced apart locations on the longitudinal axis of the tubular stent, wherein the anti-paravalvular leakage component has an expanded configuration in which the plurality of self-expanding segments curve radially away from the outer surface of the tubular stent and are oblique to the outer surface of the tubular stent such that a plane defined by each self-expanding segment is non-perpendicular with respect to a tangential plane of the tubular stent taken through the first and second attachments points.
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Accused Products
Abstract
A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.
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Citations
20 Claims
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1. A transcatheter valve prosthesis comprising:
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a tubular stent having a proximal end, a distal end and a longitudinal axis, the tubular stent having a compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve; a prosthetic valve component disposed within and secured to the tubular stent; and an anti-paravalvular leakage component coupled to and encircling an outer surface of the tubular stent, the anti-paravalvular leakage component including a plurality of self-expanding segments and an annular sealing element attached to the plurality of self-expanding segments, a first end and a second end of each self-expanding segment being attached directly to the outer surface of the tubular stent at first and second attachment points, respectively, the first and second attachment points being at axially spaced apart locations on the longitudinal axis of the tubular stent, wherein the anti-paravalvular leakage component has an expanded configuration in which the plurality of self-expanding segments curve radially away from the outer surface of the tubular stent and are oblique to the outer surface of the tubular stent such that a plane defined by each self-expanding segment is non-perpendicular with respect to a tangential plane of the tubular stent taken through the first and second attachments points. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A transcatheter valve prosthesis comprising:
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a tubular stent having a compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve; a prosthetic valve component disposed within and secured to the tubular stent; and an anti-paravalvular leakage component coupled to and encircling an outer surface of the tubular stent, the anti-paravalvular leakage component including a plurality of self-expanding segments and an annular sealing element attached to the plurality of self-expanding segments, a first end and a second end of each self-expanding segment being attached to the outer surface of the tubular stent at first and second attachment points, respectively, wherein the anti-paravalvular leakage component has an expanded configuration in which the plurality of self-expanding segments curve radially away from the outer surface of the tubular stent, and wherein at least a first self-expanding segment of the plurality of self-expanding segments at a first location on the tubular stent has a first configuration when the anti-paravalvular leakage component is in the expanded configuration and at least a second self-expanding segment of the plurality of self-expanding segments at a second location on the tubular stent has a second configuration when the anti-paravalvular leakage component is in the expanded configuration, the first and second locations being circumferentially spaced apart and the first configuration and the second configuration having different flexibilities, such that the flexibility of the anti-paravalvular leakage component at the plurality of self-expanding segments varies around the circumference of the tubular stent when the anti-paravalvular leakage component is in the expanded configuration. - View Dependent Claims (17, 18, 19)
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20. A transcatheter valve prosthesis comprising:
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a tubular stent having a compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve; a prosthetic valve component disposed within and secured to the tubular stent; and an anti-paravalvular leakage component coupled to and encircling an outer surface of the tubular stent, the anti-paravalvular leakage component including a plurality of self-expanding segments and an annular sealing element attached to the plurality of self-expanding segments, a first end and a second end of each self-expanding segment being attached to the outer surface of the tubular stent at first and second attachment points, respectively, wherein the anti-paravalvular leakage component has an expanded configuration in which the plurality of self-expanding segments curve radially away from the outer surface of the tubular stent, and wherein the plurality of self-expanding segments are spaced apart in non-equal intervals around the tubular stent such that the frequency of the self-expanding segments varies around the circumference of the tubular stent, the frequency of the self-expanding segments being the highest at portions of the tubular stent that are longitudinally aligned with native valve commissures in situ.
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Specification