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Abuse-proofed dosage form

DC
  • US 9,675,610 B2
  • Filed: 08/24/2016
  • Issued: 06/13/2017
  • Est. Priority Date: 06/17/2002
  • Status: Expired due to Term
First Claim
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1. A solid dosage form for oral administration with reduced potential for parenteral abuse, said dosage form comprising:

  • (a) one or more active ingredients having potential for abuse selected from the group consisting of hydrocodone, morphine, oxycodone, tramadol, tapentadol, and pharmaceutically acceptable salts and solvates thereof; and

    (b) one or more viscosity-increasing agents in a quantity such that an aqueous extract of a total content of the dosage form when comminuted and combined with 10 ml of water at 25°

    C. forms a gel that can be drawn up into and injected back out of a hypodermic needle having a diameter of 0.9 mm, into a further quantity of water, wherein threads of the gel injected from said needle remain visible to the naked eye in said further quantity of water at 37°

    C.

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