Methods, systems and devices for non-invasive open ventilation with gas delivery nozzles in free space

• US 9,675,774 B2
• Filed: 04/02/2010
• Issued: 06/13/2017
• Est. Priority Date: 04/02/2009
• Status: Active Grant

• Current Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Original Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Inventors: Kapust, Gregory, Wondka, Anthony D., Cipollone, Joseph, Allum, Todd, Eghbal, Darius, Aguirre, Joey, Gerber, Anthony
• Primary Examiner(s): Yu, Justine
• Assistant Examiner(s): Han, Mark K
• Application Number:
  US12/753,846
• Publication Number:
  US 20100252039A1
• Time in Patent Office: 2,629 Days
• Field of Search: 12820418, 12820423, 12820628, 12820713, 12820718, 600529, 600538, 600543
• CPC Class Codes: A61M 16/0003 Accessories therefor, e.g. sensors, vibrators, negative pressure
• CPC Class Codes: A61M 16/0006 with means for creating vibrations in patients' airways
• CPC Class Codes: A61M 16/0057 Pumps therefor
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/0096 High frequency jet ventilation
• CPC Class Codes: A61M 16/0493 with means for protecting the tube from damage caused by the patient's teeth, e.g. bite block
• CPC Class Codes: A61M 16/0605 Means for improving the adaptation of the mask to the patient
• CPC Class Codes: A61M 16/0622 having an underlying cushion
• CPC Class Codes: A61M 16/0666 Nasal cannulas or tubing devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02
• CPC Class Codes: A61M 16/0677 Gas-saving devices therefor
• CPC Class Codes: A61M 16/0683 Holding devices therefor
• CPC Class Codes: A61M 16/0688 by means of an adhesive
• CPC Class Codes: A61M 16/0825 with ball-sockets
• CPC Class Codes: A61M 16/0841 for sampling
• CPC Class Codes: A61M 16/0858 Pressure sampling ports
• CPC Class Codes: A61M 16/0875 Connecting tubes
• CPC Class Codes: A61M 16/0883 Circuit type
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 16/127 : by Venturi effect, i.e. entrainment mixers
• CPC Class Codes: A61M 16/16 : Devices to humidify the respiration air A61M16/1045 takes precedence
• CPC Class Codes: A61M 16/201 : Controlled valves
• CPC Class Codes: A61M 16/208 : Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 2016/0015 : inhalation detectors
• CPC Class Codes: A61M 2016/0021 : with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0024 : with an on-off output signal, e.g. from a switch
• CPC Class Codes: A61M 2016/0027 : pressure meter
• CPC Class Codes: A61M 2016/0036 : in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0661 : with customised shape
• CPC Class Codes: A61M 2202/0007 : introduced into the body
• CPC Class Codes: A61M 2202/0208 : Oxygen
• CPC Class Codes: A61M 2202/03 : Gases in liquid phase, e.g. cryogenic liquids
• CPC Class Codes: A61M 2205/0205 : Materials having antiseptic or antimicrobial properties, e.g. silver compounds, rubber with sterilising agent
• CPC Class Codes: A61M 2205/17 : with redundant control systems
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2230/40 : Respiratory characteristics

Abstract

A non-invasive ventilation system may include an interface. The interface may include at least one gas delivery jet nozzle adapted to be positioned in free space and aligned to directly deliver ventilation gas into an entrance of a nose. The at least one gas delivery jet nozzle may be connected to a pressurized gas supply. The ventilation gas may entrain ambient air to elevate lung pressure, elevate lung volume, decrease the work of breathing or increase airway pressure, and wherein the ventilation gas is delivered in synchrony with phases of breathing. A support for the at least one gas delivery jet nozzle may be provided. A breath sensor may be in close proximity to the entrance of the nose. A patient may spontaneous breathe ambient air through the nose without being impeded by the interface.

Claims

1. A non-invasive ventilation system for providing ventilation support to a patient via a nostril, the system comprising:

a gas source;

a gas delivery circuit;

a nasal interface adapted to communicate with the patient'"'"'s nostril while allowing the patient to breathe normally and freely from the ambient surroundings, the nasal interface comprising;

an outer tube adapted for at least partial insertion in the patient'"'"'s nostril, the outer tube having an inlet open to ambient air defining an inlet diameter, an outlet, and a jet pump throat between the inlet and the outlet defining a jet pump throat diameter, the outer tube having a constantly tapering internal diameter from the inlet to the jet pump throat; and

at least one jet nozzle in fluid communication with the gas delivery circuit and the gas source and having a distal tip disposed outside the inlet of the outer tube, the at least one jet nozzle being configured to deliver ventilation gas into the inlet of the outer tube at a velocity sufficient to define a jet profile, the diameter of the jet profile at the inlet being substantially less than the inlet diameter, the diameter of the jet profile at the jet pump throat substantially equaling the jet pump throat diameter;

wherein when ventilation gas is delivered via the at least one jet nozzle into the inlet of the outer tube at a velocity sufficient to define the jet profile, an entrainment area is defined by the cross-sectional area of the inlet outside of the diameter of the jet profile, the entrainment area providing ventilation support by entraining ambient air into the outer tube.

2. The system of claim 1, wherein the gas delivery circuit is adapted to pass along one side of a face of the patient.

3. The system of claim 2, further comprising a sensing tube circuit adapted to pass along an opposite side of the face of the patient.

4. The system of claim 1, wherein the at least one jet nozzle is positioned such that the jet of ventilation gas is delivered into the inlet of the outer tube within 10 degrees of alignment in parallel with the axial centerline of the outer tube.

5. The system of claim 1, wherein ventilation gas is delivered during inspiration.

6. The system of claim 1, wherein the at least one jet nozzle is aligned with a positioning arm.

7. The system of claim 1, wherein the at least one jet nozzle is integrated with the outer tube in a manifold.

8. The system of claim 7, wherein the manifold further comprises the gas delivery circuit and a sensing tube.

9. The system of claim 7, wherein the manifold further comprises a headset.

10. The system of claim 7, further comprising at least one sensor within the manifold.

11. The system of claim 7, further comprising a sound baffle.

12. The system of claim 1, further comprising a wearable ventilator.

13. The system of claim 1, wherein the system further comprises a ventilator and a breath sensor, the ventilator having a control unit, the control unit being adapted to adjust an output of the ventilator based on information from the breath sensor.

14. The system of claim 1, further comprising a ventilator, wherein the ventilator comprises a control unit adapted to adjust an output of the ventilator, while the patient is speaking, to not be asynchronous with spontaneous breathing of the patient.

15. The system of claim 1, wherein the system further comprises a ventilator, the ventilator comprises a control unit, and the control unit comprises an apnea or hypopnea sensing system, and wherein the control unit adjusts an output of the ventilator according to the apnea or hypopnea sensing system.