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Diagnostic method and breath testing device

  • US 9,678,058 B2
  • Filed: 03/14/2012
  • Issued: 06/13/2017
  • Est. Priority Date: 09/03/2010
  • Status: Active Grant
First Claim
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1. A method of diagnosing celiac disease in a subject comprising:

  • providing a hand-held breath detector comprising a mouthpiece, a trap and a hydrogen selective sensor which operates at room temperature and detects a hydrogen concentration at levels as low as 10 ppm in a breath sample;

    using the hand-held breath detector on a subject to detect a hydrogen concentration in a fasting breath sample of the subject, wherein the fasting breath sample of the subject is taken without requiring the subject to ingest a xylose or sorbitol carbohydrate substrate within one hour to four hours of the breath test; and

    diagnosing celiac disease in the subject if the hydrogen concentration in the fasting breath sample is above a threshold concentration.

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