Biopotential signal acquisition system and method

• US 9,681,844 B2
• Filed: 06/26/2014
• Issued: 06/20/2017
• Est. Priority Date: 06/27/2013
• Status: Active Grant

• Current Assignee: IMEC International, Stichting Imec Nederland
• Original Assignee: IMEC International, Stichting Imec Nederland
• Inventors: Xu, Jiawei, Yazicioglu, Refet Firat
• Primary Examiner(s): Phan, Huy Q
• Assistant Examiner(s): FREDERIKSEN, DAVID B
• Application Number:
  US14/315,520
• Publication Number:
  US 20150005585A1
• Time in Patent Office: 1,090 Days
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/296 for electromyography [EMG]
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/398 Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts

Abstract

A biopotential signal acquisition system, comprising: a first active electrode including an integrated pre-amplifier and an analogue to digital converter; a second active electrode including an integrated pre-amplifier and an analogue to digital converter, wherein the second active electrode has variable gain; a test signal generator for generating a test signal at a test frequency and coupling the test signal to the first and/or second active electrodes; and a digital signal processor configured to: process the digital outputs of the first and second active electrodes to derive a gain control signal based on a difference between the first and second active electrode outputs at the test frequency, and apply the gain control signal to the second active electrode. The disclosure also relates to an electronic circuit or device and a biopotential signal acquisition method.

Claims

1. A biopotential signal acquisition system, comprising:

a first active electrode including an integrated pre-amplifier and an analogue to digital converter;

a second active electrode including an integrated pre-amplifier and an analogue to digital converter, wherein the second active electrode has a variable gain;

a test signal generator configured to generate a test signal at a test frequency and to couple the test signal to the first and/or second active electrodes; and

a digital signal processor configured to process the digital outputs of the first and second active electrodes to derive a gain control signal based on a difference between the first and second active electrode outputs at the test frequency, and to apply the gain control signal to the second active electrode.

2. The biopotential signal acquisition system according to claim 1, wherein the gain control signal is digital, and the second active electrode comprises a digital to analogue converter.

3. The biopotential signal acquisition system according to claim 1, wherein the digital signal processor comprises a digital band pass filter tuned to the test frequency for producing the gain control signal.

4. The biopotential signal acquisition system according to claim 1, wherein the digital signal processor comprises a digital low pass filter for removing the test signal frequency before providing a system output.

5. The biopotential signal acquisition system according to claim 1, wherein the biopotential signal acquisition system further comprises at least a third active electrode including an integrated pre-amplifier and an analogue to digital converter, wherein the third active electrode has variable gain and is coupled to the test signal;

and wherein the digital signal processor is further configured to process the digital outputs of the first and third active electrodes to derive a gain control signal based on a difference between the first and third active electrode outputs at the test frequency, and to apply the gain control signal to the third active electrode.

6. The biopotential signal acquisition system according to claim 1, further comprising averaging means for averaging the outputs of the first and second active electrodes to derive a digital signal representing a common mode signal.

7. The biopotential signal acquisition system according to claim 5, further comprising averaging means for averaging the outputs of the second and third and any additional electrodes to derive a digital signal representing a common mode signal.

8. The biopotential signal acquisition system according to claim 6, further comprising a digital to analogue converter for converting the derived digital common mode signal into an analogue common mode feedback signal that is provided to the active electrodes.

9. The biopotential signal acquisition system according to claim 7, further comprising a digital to analogue converter for converting the derived digital common mode signal into an analogue common mode feedback signal that is provided to the active electrodes.

10. The biopotential signal acquisition system according to claim 7, wherein each active electrode comprises subtraction means for subtracting an AC part of the common mode feedback signal from the input signal to the respective active electrode.

11. An electronic circuit or device comprising a biopotential signal acquisition system as recited in claim 1.

12. A biopotential signal acquisition method, comprising:

capturing a first biopotential signal using a first active electrode comprising an integrated pre-amplifier and an analogue to digital converter;

capturing a second biopotential signal using a second active electrode comprising an integrated pre-amplifier and an analogue to digital converter, wherein the second active electrode has a variable gain;

generating a test signal at a test frequency and coupling the test signal to the first and/or second active electrodes; and

processing the digital outputs of the first and second active electrodes to derive a gain control signal based on a difference between the first and second active electrode outputs at the test frequency, and applying the gain control signal to the second active electrode.

13. The biopotential signal acquisition method according to claim 12, wherein the gain control signal is digital, and the method further includes, in the second active electrode, converting the gain control signal to an analogue signal and using this gain control signal to set the gain of the pre-amplifier of the second active electrode.

14. The biopotential signal acquisition method according to claim 12, wherein the method further comprises:

capturing at least a third biopotential signal using a third active electrode comprising an integrated pre-amplifier and an analogue to digital converter, wherein the second active electrode has a variable gain;

further coupling the test signal to the third active electrode; and

further processing the digital outputs of the first and third active electrodes to derive a gain control signal based on a difference between the first and third active electrode outputs at the test frequency, and further applying the gain control signal to the third active electrode.

15. The biopotential signal acquisition method according to claim 12, further comprising averaging the outputs of the first and second active electrodes to derive a digital signal representing a common mode signal, converting the derived digital common mode signal into an analogue common mode feedback signal and providing the analogue common mode feedback signal to the first and second active electrodes.

16. The biopotential signal acquisition method according to claim 14, wherein the method further comprises averaging the outputs of the second, third, and any additional active electrodes to derive a digital signal representing a common mode signal, converting the derived digital common mode signal into an analogue common mode feedback signal and providing the analogue common mode feedback signal to each active electrode.