Hemoglobin contrast in magneto-motive optical doppler tomography, optical coherence tomography, and ultrasound imaging methods and apparatus
First Claim
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1. A system for imaging, comprising:
- a magnet for applying a magnetic field to the vessels to be imaged, wherein the applied magnetic field interacts with hemoglobin within the vasculature; and
an optical coherence tomography apparatus for detecting magnetic movement of the hemoglobin within the vasculature, wherein optical coherence tomography apparatus includes a tunable laser source in the optical frequency domain and an optical clock to sample interference fringe data uniformly spaced in the optical frequency domain.
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Abstract
Provided herein are systems, methods, and compositions for the use of optical coherence tomography for detection of cells.
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Citations
20 Claims
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1. A system for imaging, comprising:
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a magnet for applying a magnetic field to the vessels to be imaged, wherein the applied magnetic field interacts with hemoglobin within the vasculature; and an optical coherence tomography apparatus for detecting magnetic movement of the hemoglobin within the vasculature, wherein optical coherence tomography apparatus includes a tunable laser source in the optical frequency domain and an optical clock to sample interference fringe data uniformly spaced in the optical frequency domain. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for imaging a blood flow, comprising:
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applying a magnetic field to the blood flow with a magnet, wherein the blood flow comprises a plurality of hemoglobin molecules and wherein the magnetic field interacts with the hemoglobin to cause a change in the blood flow; and detecting the blood flow by detecting the change in the blood flow caused by the interaction with the hemoglobin molecules with the magnetic field, wherein the change is detected using an optical coherence tomography system, wherein optical coherence tomography apparatus includes a tunable laser source in the optical frequency domain and an optical clock to sample interference fringe data uniformly spaced in the optical frequency domain. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
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Specification