Occlusive devices and methods of use

• US 9,687,245 B2
• Filed: 03/15/2013
• Issued: 06/27/2017
• Est. Priority Date: 03/23/2012
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Molaei, Masoud, Nageswaran, Ashok, Griffin, Stephen, Losordo, Michael Louis, Davidson, Jim
• Primary Examiner(s): Shi, Katherine M
• Assistant Examiner(s): GABR, MOHAMED GAMIL
• Application Number:
  US13/841,836
• Publication Number:
  US 20130253572A1
• Time in Patent Office: 1,565 Days
• Field of Search: 606200, 606198, 606194, 606191, 606159, 606151
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device

Abstract

An aneurysm therapy system, can include a catheter and an occlusive device. The catheter can have a proximal end, a distal end, and a lumen extending between the proximal and distal ends. The proximal end can include a self-expanding distal section, and the distal section can comprise a coil portion. The occlusive device can be disposed within the lumen and configured to reside in the aneurysm to restrict fluid flow within the aneurysm.

Claims

1. An aneurysm therapy system, comprising, in combination:

a catheter having a proximal end, a distal end, and a lumen extending between the proximal and distal ends, wherein the distal end of the catheter is configured to be positioned at or near an aneurysm; and

an occlusive device, disposed within the lumen and configured to reside in the aneurysm to restrict fluid flow within the aneurysm, the occlusive device comprising;

a distal section comprising a coil having an outer diameter, a coil length extending from a proximal end of the coil to a distal end of the coil, and a coil flexibility, the coil distal end being a free, terminal distal end of the coil;

a self-expanding braided proximal section comprising a closed distal end and a free, terminal proximal end, the braided proximal section having (i) a radially compressed state with a first diameter when positioned within the delivery lumen and (ii) a radially expanded state with a second diameter, greater than the coil diameter, when unconstrained, (iii) a braid length greater than the coil length, and (iv) a braid flexibility less than the coil flexibility per unit length; and

a tubular transition member, coupled to the coil proximal end and to the closed distal end of the braided proximal section, the transition member having (i) a transition length greater than or equal to the coil length, (ii) a transition flexibility less than the coil flexibility per unit length, and (iii) a cross-sectional profile that is less than an expanded cross-sectional profile of the braided proximal section,

wherein the occlusive device is disposed within the catheter lumen such that the proximal section is proximal of the distal section along a longitudinal dimension of the occlusive device so that, during delivery of the occlusive device to the aneurysm, the distal section emerges from the distal end of the catheter before the proximal section, and

wherein the proximal section is configured to expand to the expanded cross-sectional profile during advancement out of the distal end of the catheter, and the distal section is configured to distribute, along at least a portion of the coil length, a force of the advancement along an aneurysm interior wall.

2. The system of claim 1, wherein the coil outer diameter is substantially constant.

3. The system of claim 1, wherein the distal section is configured to abut the aneurysm interior wall to direct the distal most proximal section as the proximal section is advanced into the aneurysm.

4. The system of claim 1, wherein the first diameter is substantially the same as the coil diameter when the proximal section is in the delivery lumen.

5. The system of claim 1, wherein the distal section comprises a curved distal end.

6. The system of claim 5, wherein a maximum radius of curvature of the distal section is less than a maximum radius of curvature of the proximal section.

7. The system of claim 1, wherein the proximal section has a secondary preset, three-dimensional shape when in the radially expanded state.

8. The system of claim 1, wherein the braid length is from about 50 mm to about 150 mm.

9. The system of claim 1, wherein the coil length is from about 30 mm to about 40 mm.

10. The system of claim 1, wherein the second diameter is from about 2.8 to about 5.8 times the first diameter, and the first diameter is from about 0.017 inches and about 0.021 inches.

11. The system of claim 1, wherein the proximal section comprises a first bend within a first plane and a second bend out of the first plane.

12. The system of claim 1, wherein a wall of the proximal section comprises pores having an average pore size from about 25 microns to about 250 microns.

13. The system of claim 1, further comprising a shaping member extending within the proximal section and coupled to the proximal section.

14. The system of claim 1, wherein the proximal section is tubular.

15. The system of claim 1, wherein at least a portion of the transition member is tapered.