Arterial blood pressure monitoring devices, systems and methods for use while pacing
First Claim
1. For use with an implantable system, a method for monitoring a patient'"'"'s arterial blood pressure, the method comprising:
- (a) producing a ventricular pacing signal, which includes a plurality of ventricular pacing pulses, and pacing a patient'"'"'s heart using the ventricular pacing signal and at least one electrode implanted within or on the patient'"'"'s heart;
(b) using an implanted sensor or implanted electrodes, remote from the patient'"'"'s heart, to obtain a signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart while the patient'"'"'s heart is being paced;
(c) detecting one or more predetermined features of the signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart obtained at step (b);
(d) determining one or more metrics indicative of pulse arrival time (PAT), by determining a time from a ventricular pacing pulse of the ventricular pacing signal to one or more of the predetermined features of the signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart detected at step (c); and
(e) estimating the patient'"'"'s arterial blood pressure based on at least one of the one or more metrics indicative of PAT.
1 Assignment
0 Petitions
Accused Products
Abstract
Provided herein are implantable systems, and methods for use therewith, for monitoring a patient'"'"'s arterial blood pressure while a patient'"'"'s heart is being paced. A signal (e.g., PPG or IPG signal) indicative of changes in arterial blood volume remote from the patient'"'"'s heart is obtained using a sensor or electrodes that are implanted remote from the patient'"'"'s heart. One or more metrics indicative of pulse arrival time (PAT) are determined, where each metric can be determined by determining a time from a paced cardiac event to one or more predetermined features of the signal indicative of changes in arterial blood volume. Based on at the metric(s) indicative of PAT, arterial blood pressure is estimated, which can include determining values indicative of systolic blood pressure, diastolic blood pressure, pulse pressure and/or mean arterial blood pressure, and/or changes in such values.
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Citations
16 Claims
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1. For use with an implantable system, a method for monitoring a patient'"'"'s arterial blood pressure, the method comprising:
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(a) producing a ventricular pacing signal, which includes a plurality of ventricular pacing pulses, and pacing a patient'"'"'s heart using the ventricular pacing signal and at least one electrode implanted within or on the patient'"'"'s heart; (b) using an implanted sensor or implanted electrodes, remote from the patient'"'"'s heart, to obtain a signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart while the patient'"'"'s heart is being paced; (c) detecting one or more predetermined features of the signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart obtained at step (b); (d) determining one or more metrics indicative of pulse arrival time (PAT), by determining a time from a ventricular pacing pulse of the ventricular pacing signal to one or more of the predetermined features of the signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart detected at step (c); and (e) estimating the patient'"'"'s arterial blood pressure based on at least one of the one or more metrics indicative of PAT. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. An implantable system, comprising:
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a pulse generator configured to produce a ventricular pacing signal including a plurality of ventricular pacing pulses that are deliverable to a patient'"'"'s heart using at least one electrode implanted within or on the patient'"'"'s heart; a plethysmography sensor configured to obtain a signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart while the patient'"'"'s heart is being paced with the voltage sufficient to cause capture; an arterial blood pressure monitor configured to detect one or more predetermined features of the signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart; determine one or more metrics indicative of pulse arrival time (PAT) based on times of a ventricular pacing pulse of the ventricular pacing signal and at least one of the one or more detected predetermined features of the signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart; and estimate the patient'"'"'s arterial blood pressure based on at least one of the one or more metrics indicative of PAT. - View Dependent Claims (9, 10, 11, 12, 13, 15)
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14. The implantable system of 13, wherein the arterial blood pressure monitor is configured to determine at least one of the metrics indicative of PAT by determining a time from a ventricular pacing pulse of the ventricular pacing signal to a detected predetermined feature of the signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart, minus the determined value indicative of EMD.
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16. For use with an implantable system, a method for monitoring a patient'"'"'s arterial blood pressure, the method comprising:
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(a) pacing a patient'"'"'s heart using a ventricular pacing pulse of a ventricular pacing signal; (b) obtaining a photoplethysmography (PPG) signal or an impedance plethysmography (IPG) signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart while the patient'"'"'s heart is being paced; (c) detecting one or more predetermined features of the PPG or IPG signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart obtained at step (b); (d) determining one or more metrics indicative of pulse arrival time (PAT), by determining a time from a ventricular pacing pulse of the ventricular pacing signal to one or more of the predetermined features of the PPG or IPG signal indicative of changes in arterial blood volume remote from the patient'"'"'s heart detected at step (c); and (e) estimating the patient'"'"'s arterial blood pressure based on at least one of the one or more metrics indicative of PAT.
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Specification