Methods and apparatus for the planning and delivery of radiation treatments
First Claim
1. A system for planning delivery of a radiation dose to a target region within a subject, the system comprising a processor, the processor configured to:
- initialize a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a treatment radiation source and the subject, wherein initializing the first plurality of control points comprises assigning, to each of the first plurality of control points, one or more axis positions which specify a position of the treatment radiation source relative to the subject;
specify a second plurality of control points along the trajectory, the second plurality of control points comprising a larger number of control points than the first plurality of control points; and
iteratively optimize a simulated dose distribution relative to a set of one or more optimization goals over the second plurality of control points to thereby determine a radiation delivery plan by assigning each of the second plurality of control points optimized values for a plurality of radiation delivery parameters;
wherein the one or more axis positions comprise an angle of a gantry supporting the treatment radiation source;
wherein the optimized values for the plurality of radiation delivery parameters specify both, beam shape of the treatment radiation source and beam intensity of the treatment radiation source;
wherein the optimized values for the plurality of radiation delivery parameters specify radiation output rates for the treatment radiation source;
wherein the optimized values for the plurality of radiation delivery parameters specify leaf configurations for a multi-leaf collimator through which a beam of the treatment radiation source is directed;
wherein the trajectory comprises a plurality of arcs, each arc involving relative movement between the treatment radiation source and the subject within a corresponding plane;
wherein, between successive ones of the plurality of arcs, the trajectory comprises inter-arc relative movement between the treatment radiation source and the subject, the inter-arc relative movement comprising movement such that the corresponding planes associated with each arc intersect one another.
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Accused Products
Abstract
Systems for planning delivery of radiation dose to a target region within a subject comprise a processor configured to: initialize a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a radiation source and the subject, wherein initializing the first plurality of control points comprises assigning, to each the first plurality of control points, one or more axis positions which specify a position of the radiation source relative to the subject; specify a second plurality of control points along the trajectory, the second plurality of control points comprising a larger number of control points than the first plurality of control points; and iteratively optimize a simulated dose distribution over the second plurality of control points to thereby determine a radiation delivery plan by assigning each of the second plurality of control points optimized values for one or more radiation delivery parameters.
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Citations
23 Claims
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1. A system for planning delivery of a radiation dose to a target region within a subject, the system comprising a processor, the processor configured to:
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initialize a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a treatment radiation source and the subject, wherein initializing the first plurality of control points comprises assigning, to each of the first plurality of control points, one or more axis positions which specify a position of the treatment radiation source relative to the subject; specify a second plurality of control points along the trajectory, the second plurality of control points comprising a larger number of control points than the first plurality of control points; and iteratively optimize a simulated dose distribution relative to a set of one or more optimization goals over the second plurality of control points to thereby determine a radiation delivery plan by assigning each of the second plurality of control points optimized values for a plurality of radiation delivery parameters; wherein the one or more axis positions comprise an angle of a gantry supporting the treatment radiation source; wherein the optimized values for the plurality of radiation delivery parameters specify both, beam shape of the treatment radiation source and beam intensity of the treatment radiation source; wherein the optimized values for the plurality of radiation delivery parameters specify radiation output rates for the treatment radiation source; wherein the optimized values for the plurality of radiation delivery parameters specify leaf configurations for a multi-leaf collimator through which a beam of the treatment radiation source is directed; wherein the trajectory comprises a plurality of arcs, each arc involving relative movement between the treatment radiation source and the subject within a corresponding plane; wherein, between successive ones of the plurality of arcs, the trajectory comprises inter-arc relative movement between the treatment radiation source and the subject, the inter-arc relative movement comprising movement such that the corresponding planes associated with each arc intersect one another. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A system for planning delivery of a radiation dose to a target region within a subject, the system comprising a processor, the processor configured to:
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initialize a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a treatment radiation source and the subject, wherein initializing the first plurality of control points comprises assigning, to each of the first plurality of control points, one or more axis positions which specify a position of the treatment radiation source relative to the subject; specify a second plurality of control points along the trajectory, the second plurality of control points comprising a larger number of control points than the first-plurality of control points; and iteratively optimize a simulated dose distribution relative to a set of one or more optimization goals over the second plurality of control points to thereby determine a radiation delivery plan by assigning each of the second plurality of control points optimized values for a plurality of radiation delivery parameters; wherein the one or more axis positions comprise an angle of a gantry supporting the treatment radiation source; wherein the optimized values for the plurality of radiation delivery parameters specify both beam shape of the treatment radiation source and beam intensity of the treatment radiation source; wherein the optimized values for the plurality of radiation delivery parameters specify radiation output rates for the treatment radiation source; wherein the optimized values for the plurality of radiation delivery parameters specify leaf configurations for a multi-leaf collimator through which a beam of the treatment radiation source is directed; wherein the trajectory comprises a plurality of arcs, each arc involving relative movement between the treatment radiation source and the subject within a corresponding plane; wherein, between successive ones of the plurality of arcs, the trajectory comprises inter-arc relative movement between the treatment radiation source and the subject, the inter-arc relative movement comprising movement such that the corresponding planes associated with each arc are parallel with one another. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification