Monitoring method and apparatus

• US 9,689,866 B2
• Filed: 01/29/2013
• Issued: 06/27/2017
• Est. Priority Date: 12/18/2003
• Status: Active Grant

• Current Assignee: Inverness Medical Switzerland GmbH (Abbott Laboratories)
• Original Assignee: Inverness Medical Switzerland GmbH (Abbott Laboratories)
• Inventors: Reay, Marika, Sheard, Paul
• Primary Examiner(s): Menon, Krishnan S
• Assistant Examiner(s): Gerido, Dwan A
• Application Number:
  US13/752,690
• Publication Number:
  US 20130203158A1
• Time in Patent Office: 1,610 Days
• Field of Search: 422 681
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: G01N 2333/58 Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
• CPC Class Codes: G01N 2800/32 Cardiovascular disorders
• CPC Class Codes: G01N 33/5302 Apparatus specially adapted for immunological test procedures
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment
• CPC Class Codes: Y10T 436/11 Automated chemical analysis

Abstract

A device for remote management of patients suffering from heart failure and hypertension can measure one or more biomarker. The device aids in monitoring the efficacy and safety of treatment in such patients.

Claims

1. A device for monitoring cardiac health comprising;

a testing cartridge comprising a sample input and an assay for a brain natriuretic peptide in a sample taken from a patient who has hypertension;

a brain natriuretic peptide detector that measures a level of a brain natriuretic peptide with the testing cartridge, and based on the measured level of brain natriuretic peptide, detects changes in the level of brain natriuretic peptide;

a recorder that records a level of one or more biomarkers including the measured level of brain natriuretic peptide and patient input(s) regarding sign(s) and symptom(s) of a disease to set or refine a baseline level of brain natriuretic peptide for the patient;

and

a communication port connecting the recorder and the brain natriuretic peptide detector, wherein the communication port transmits a personalized recorded result or a personalized measured result based on at least the measured level of brain natriuretic peptide and the baseline brain natriuretic peptide level for the patient in combination with a patient'"'"'s medical records, to a health care provider, provides feedback to the patient and alerts the patient to the patient'"'"'s test results.

2. The device of claim 1, wherein the brain natriuretic peptide is active BNP.

3. The device of claim 1, wherein the brain natriuretic peptide is N-BNP.

4. The device of claim 1, wherein the testing cartridge is disposable.

5. The device of claim 1, wherein the testing cartridge allows the sequential or serial measurement of a marker of left ventricular volume overload.

6. The device of claim 1, wherein the testing cartridge allows the sequential or serial measurement of a marker of myocardial stretch.

7. The device of claim 1, wherein the testing cartridge allows the sequential or serial measurement of a marker of renal function.

8. A device for monitoring cardiac health comprising;

a testing cartridge comprising a sample input and an assay for a brain natriuretic peptide in a sample taken from a patient who has survived a first myocardial infarction;

a brain natriuretic peptide detector that measures a level of a brain natriuretic peptide with the testing cartridge, and based on the measured level of brain natriuretic peptide, detects changes in the level of brain natriuretic peptide;

a recorder that records a level of one or more biomarkers including the measured level of brain natriuretic peptide and patient input(s) regarding sign(s) and symptom(s) of a disease to set or refine a baseline level of brain natriuretic peptide for the patient;

a communication port connecting the recorder and the brain natriuretic peptide detector, wherein the communication port transmits a personalized recorded result or a personalized measured result based on at least the measured level of brain natriuretic peptide and the baseline brain natriuretic peptide level for the patient in combination with a patient'"'"'s medical records, to a health care provider, provides feedback to a patient and alerts the patient to the patient'"'"'s test results.

9. A device for monitoring cardiac health comprising;

a testing cartridge comprising a sample input and an assay for a brain natriuretic peptide in a sample taken from a patient who is at risk for future myocardial infarction;

a brain natriuretic peptide detector that measures a level of a brain natriuretic peptide with the testing cartridge, and based on the measured level of brain natriuretic peptide, detects changes in the level of brain natriuretic peptide;

a recorder that records a level of one or more biomarkers including the measured level of brain natriuretic peptide and patient input(s) regarding sign(s) and symptom(s) of a disease to set or refine a baseline level of brain natriuretic peptide for the patient and;

a communication port connecting the recorder and the brain natriuretic peptide detector, wherein the communication port transmits a personalized recorded result or a personalized measured result based on at least the measured level of brain natriuretic peptide and the baseline brain natriuretic peptide level for the patient in combination with a patient'"'"'s medical records, to a health care provider, provides feedback to a patient and alerts the patient to the patient'"'"'s test results.