Apparatus and methods for administering treatment within a bodily duct of a patient

• US 9,692,557 B2
• Filed: 01/08/2016
• Issued: 06/27/2017
• Est. Priority Date: 02/04/2015
• Status: Active Grant

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Stryker Corporation, Stryker European Holdings I, LLC (Stryker Corporation)
• Inventors: Murphy, Murtagh M.
• Primary Examiner(s): Price, Nathan R
• Assistant Examiner(s): Lee, Weng
• Application Number:
  US14/991,032
• Publication Number:
  US 20160220793A1
• Time in Patent Office: 536 Days
• CPC Class Codes: A61M 2025/0079 Separate user-activated means, e.g. guidewires, guide tubes, balloon catheters or sheaths, for sealing off an orifice, e.g. a lumen or side holes, of a catheter
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1081 having sheaths or the like for covering the balloon but not forming a permanent part of the balloon, e.g. retractable, dissolvable or tearable sheaths
• CPC Class Codes: A61M 2025/1086 having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
• CPC Class Codes: A61M 25/0051 made from fenestrated or weakened tubing layer
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0074 Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
• CPC Class Codes: A61M 25/0108 using radio-opaque or ultrasound markers
• CPC Class Codes: A61M 25/10185 Valves
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: H03M 13/09 Error detection only, e.g. using cyclic redundancy check [CRC] codes or single parity bit
• CPC Class Codes: H03M 13/1165 QC-LDPC codes as defined for the digital video broadcasting [DVB] specifications, e.g. DVB-Satellite [DVB-S2]
• CPC Class Codes: H03M 13/152 Bose-Chaudhuri-Hocquenghem [BCH] codes
• CPC Class Codes: H03M 13/253 with concatenated codes
• CPC Class Codes: H03M 13/255 with Low Density Parity Check [LDPC] codes
• CPC Class Codes: H03M 13/271 Row-column interleaver with permutations, e.g. block interleaving with inter-row, inter-column, intra-row or intra-column permutations
• CPC Class Codes: H03M 13/2778 Interleaver using block-wise interleaving, e.g. the interleaving matrix is sub-divided into sub-matrices and the permutation is performed in blocks of sub-matrices
• CPC Class Codes: H03M 13/2906 using block codes H03M13/2957 takes precedence
• CPC Class Codes: H03M 13/618 Shortening and extension of codes
• CPC Class Codes: H03M 13/6356 : by repetition or insertion of dummy data, i.e. rate reduction
• CPC Class Codes: H03M 13/6362 : by puncturing
• CPC Class Codes: H04L 1/0041 : Arrangements at the transmitter end
• CPC Class Codes: H04L 1/0057 : Block codes H04L1/0061, H04L1/0064 take precedence
• CPC Class Codes: H04L 1/0071 : Use of interleaving interleaving per se H03M13/27
• CPC Class Codes: H04L 12/18 : for broadcast or conference , e.g. multicast
• CPC Class Codes: H04L 12/1886 : with traffic restrictions for efficiency improvement, e.g. involving subnets or subdomains
• CPC Class Codes: H04L 2001/0093 : Point-to-multipoint
• CPC Class Codes: H04L 5/0053 : Allocation of signaling, i.e. of overhead other than pilot signals
• CPC Class Codes: H04W 4/06 : Selective distribution of broadcast services, e.g. multimedia broadcast multicast service [MBMS]; Services to user groups; One-way selective calling services

Abstract

Apparatus and methods for administering treatment within a bodily duct of a patient. According to one implementation a treatment catheter having an expandable structure disposed at an end thereof is provided that includes an elongate hollow shaft having a one or more first through holes and one or more second through holes spaced axial apart, the one or more first through holes residing beneath the expandable structure. A sleeve positioned along an outer surface of the hollow shaft is moveable between first and second axial positions to respectively permit or inhibit the flow of a treatment agent through the one or more second through holes into the bodily duct. An elongate wire having a seal unit is positioned within an inner lumen of the hollow shaft. The seal unit is moveable between first and second axial positions to respectively permit or inhibit the flow of an inflation medium between a cavity of the expandable structure and the inner lumen of the hollow shaft through the one or more first through holes.

Claims

1. A treatment catheter for placement in a bodily duct of a patient, the treatment catheter comprising:

an expandable structure,

an elongate hollow shaft having a wall with a first through hole and a second through hole, the first through hole spaced axially apart from the second through hole, the elongate hollow shaft having a proximal end portion and a distal end portion, the expandable structure being disposed about the distal end portion of the elongate hollow shaft such that the first through hole resides beneath the expandable structure, the second through hole being located proximal to the expandable structure,

a sleeve positioned along an outer surface of the elongate hollow shaft moveable between first and second axial positions to respectively permit and inhibit the flow of a treatment agent through the second through hole into the bodily duct,

an elongate wire having a seal unit positioned within an inner lumen of the elongate hollow shaft, the seal unit positioned at least partially beneath the expandable structure and being moveable between first and second axial positions to respectively permit and inhibit the flow of an inflation medium between a cavity of the expandable structure and the inner lumen of the hollow shaft through the first through hole, the first axial position being located distal to the second axial position.

2. The treatment catheter according to claim 1, wherein a cross-sectional area of the elongate wire located proximal to the seal unit is less than a cross-sectional area of the inner lumen of the elongate hollow shaft.

3. The treatment catheter according to claim 1, wherein the elongate hollow shaft is made of a metal.

4. The treatment catheter of claim 3, wherein the proximal end portion of the elongate hollow shaft comprises a hypotube.

5. The treatment catheter according to claim 3, wherein the elongate hollow shaft has an outer diameter of between 0.025 inches and 0.035 inches.

6. The treatment catheter according to claim 4, wherein the elongate hollow shaft has an outer diameter of between 0.025 inches and 0.035 inches.

7. The treatment catheter according to claim 6, wherein the wall of the elongate hollow shaft has a thickness between 0.004 inches and 0.006 inches.

8. The treatment catheter according to claim 5, wherein the distal portion of the elongate hollow shaft comprises a plurality of cuts extending into the outer surface to enhance the flexibility of the distal portion.

9. The treatment catheter according to claim 1, wherein a compression fit exists between an outer surface of the seal unit and an inner surface of the elongate hollow shaft.

10. The treatment catheter according to claim 1, wherein a compression fit exists between the sleeve and the outer surface of the elongate hollow shaft.

11. The treatment catheter according to claim 1, wherein the seal unit comprises an elastomer material disposed along a length of an outer surface of the elongate wire.

12. The treatment catheter according to claim 11, wherein the elastomer material resides within a recess in the outer surface of the elongate wire.

13. The treatment catheter according to claim 11, wherein the outer surface of the elongate wire is roughened to enhance an adhesion of the elastomer to the elongate wire.

14. The treatment catheter according to claim 11, wherein the elastomer material is silicone.

15. The treatment catheter according to claim 1, wherein the seal unit comprises a proximal end and a distal end and the elongate wire is provided with a first radiopaque marker adjacent the proximal end of the seal unit and with a second radiopaque marker adjacent the distal end of the seal unit.

16. The treatment catheter according to claim 1, wherein a distal end of the sleeve is provided with a third radiopaque marker.

17. The treatment catheter according to claim 15, wherein a distal end of the sleeve is provided with a third radiopaque marker.

18. The treatment catheter according to claim 17, wherein the distal end of the expandable structure is provided with a fourth radiopaque marker.

19. The treatment catheter according to claim 1, wherein one or more of the elongate wire, seal unit and distal end of elongate hollow shaft is provided with stop elements to delimit the axial movement of the seal unit between the first and second axial positions.

20. The treatment catheter according to claim 1, wherein the elongate wire comprises an end segment that extends distally to the seal unit, the end segment having a length sufficient for the treatment catheter to be self-guided through at least a portion of the bodily duct.

21. The treatment catheter according to claim 1, wherein the expandable structure is a balloon that comprises an inflatable membrane.

22. The treatment catheter according to claim 21, wherein the balloon has a length of between 2 to 10 millimeters.

23. The treatment catheter according to claim 21, wherein at least a portion of the expandable membrane located along the proximal portion of the balloon is porous.

24. The treatment catheter according to claim 21, wherein at least a portion of the expandable membrane located along the proximal portion of the balloon has one or more through openings.

25. The treatment catheter according to claim 1, wherein the expandable structure is an expandable cage with a cover disposed over an external surface of the expandable cage, the cover being made of a material capable of occluding the passage of a fluid there through.

26. The treatment catheter according to claim 25, wherein the expandable cage comprises a proximal portion and a distal portion, at least a portion of the cover overlying the proximal portion is porous.

27. The treatment catheter according to claim 25, wherein the expandable cage comprises a proximal portion and a distal portion, at least a portion of the cover overlying the proximal portion has one or more through openings.