Dual GLP-1/glucagon receptor agonists
First Claim
Patent Images
1. A peptidic compound of formula (I):
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R1—
Z—
R2
(I),or a salt or solvate thereof,wherein Z is a peptide moiety of formula (II);
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Abstract
The present invention relates to exendin-4 derivatives and their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as reduction of excess food intake.
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22 Claims
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1. A peptidic compound of formula (I):
-
R1—
Z—
R2
(I),or a salt or solvate thereof, wherein Z is a peptide moiety of formula (II); - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification