UV curable solventless antimicrobial compositions
First Claim
1. An antimicrobial;
- ultraviolet (UV) curable spray comprising;
an adhesive comprising an oligomer, a monomer, and a photoinitiator; and
an insoluble non-metallic antimicrobial agent comprising a plurality of particles, each of the particles having a particle size less than 10 μ
m;
wherein the antimicrobial, ultraviolet (UV) curable spray does not comprise a rheology modifier, wherein a concentration of the antimicrobial agent is less than 8.9 parts by weight in 100 parts by weight of the coating, wherein the antimicrobial spray has a viscosity from approximately 5 centipose to approximately 500 centipose.
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Accused Products
Abstract
Antimicrobial compositions and methods are disclosed. The antimicrobial compositions are particularly useful in providing antimicrobial capability to a wide-range of medical devices. In one aspect the invention relates a UV curable antimicrobial coating comprising a UV curable composition comprising an oligomer, a momoner, and a photoinitiator which are together capable of forming a UV curable polymer composition. The compositions also include insoluble antimicrobial agents, which may be selected from a wide array of agents. The insoluble antimicrobial agents include a particle size less than 15 μm. Representative insoluble antimicrobial agents include chlorhexidine diacetate, chlorhexidine base, alexidine(dihydrochloride), silver sulfadiazene, silver citrate, triclosan, octenidine(dihydrochloride), and rifampicin.
308 Citations
11 Claims
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1. An antimicrobial;
- ultraviolet (UV) curable spray comprising;
an adhesive comprising an oligomer, a monomer, and a photoinitiator; and an insoluble non-metallic antimicrobial agent comprising a plurality of particles, each of the particles having a particle size less than 10 μ
m;wherein the antimicrobial, ultraviolet (UV) curable spray does not comprise a rheology modifier, wherein a concentration of the antimicrobial agent is less than 8.9 parts by weight in 100 parts by weight of the coating, wherein the antimicrobial spray has a viscosity from approximately 5 centipose to approximately 500 centipose. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
- ultraviolet (UV) curable spray comprising;
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9. A UV curable coating composition comprising:
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a) an adhesive, comprising; an oligomer; a monomer; and a photoinitiator; b) an insoluble antimicrobial agent comprising a plurality of particles, each of the particles having a particle size less than about 15 μ
m, and provided in a concentration from less than approximately 8.9 parts by weight in 100 parts UV curable coating composition;wherein the UV curable coating comprises a viscosity from approximately 5 centipoise to approximately 500 centipoise, wherein the UV curable coating composition does not comprise a rheology modifier. - View Dependent Claims (10)
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11. A method of facilitating gradual release of an antimicrobial agent from an antimicrobial, ultraviolet (UV) curable coating on a surface of a medical device, comprising:
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providing an antimicrobial, UV curable coating composition, wherein the antimicrobial, UV curable coating composition comprises; an adhesive comprising an oligomer, a monomer, and a photoinitiator; and an insoluble non-metallic antimicrobial agent comprising a plurality of particles, each of the particles having a particle size less than 15 μ
m, wherein a concentration of the insoluble non-metallic antimicrobial agent is less than 8.9 parts by weight in 100 parts by weight of the coating,wherein the antimicrobial, UV curable coating composition does not comprise a rheology modifier and has a viscosity from approximately 5 centipose to approximately 500 centipose; and spraying the UV curable coating composition on the surface of the medical device.
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Specification