Method and system to equalizing cardiac cycle length between map points

• US 9,700,233 B2
• Filed: 05/04/2015
• Issued: 07/11/2017
• Est. Priority Date: 05/05/2014
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Nabutovsky, Yelena, Razavi, Hoda
• Primary Examiner(s): PATTON, AMANDA K
• Application Number:
  US14/703,744
• Publication Number:
  US 20150313550A1
• Time in Patent Office: 799 Days
• CPC Class Codes: A61B 5/062 using magnetic field
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/346 Analysis of electrocardiograms
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 5/7289 Retrospective gating, i.e. associating measured signals or images with a physiological event after the actual measurement or image acquisition, e.g. by simultaneously recording an additional physiological signal during the measurement or image acquisition
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence

Abstract

A method and system are provided for equalizing cycle lengths among different map points during mapping studies. Different embodiments may be applicable to different circumstances and physiological settings. A compression embodiment encapsulates the entire behavior of a map point throughout its native cycle length. A truncation and rotation embodiment, and an extension and rotation embodiment allow for a more physiologically-relevant processing of the motion data.

Claims

1. A method to analyze data of a region of interest in order to generate a cardiac map, the method comprising:

utilizing one or more processors;

acquiring data recordings of motion data at each of a select number of map points for the region of interest with a navigation system motion sensor in contact with the region of interest;

determining cycle lengths associated with cardiac events in the data recordings, wherein the determining operation includes determining a plurality of cycle lengths in connection with a first map point of the select number of map points;

equalizing cycle lengths among different map points for the region of interest;

modifying the motion data based on the equalizing operation; and

displaying the modified motion data on a display.

2. The method of claim 1, wherein the equalizing comprises performing at least one of i) a compression process to encapsulate an entire behavior of at least one map point of the select number of map points throughout a native cycle length;

ii) a truncation and rotation process;

or iii) an extension and rotation process.

3. The method of claim 1, wherein the equalizing operation includes identifying a select cycle length from the plurality of cycle lengths and down-sampling the motion data for the map points throughout the cycle lengths to produce a down sampled motion data set having a same number of motion data samples for each of the map points.

4. The method of claim 1, wherein the equalizing operation includes identifying a select cycle length from the cycle lengths and modifying the motion data to have a common number of motion data samples for each map point.

5. The method of claim 4, wherein the equalizing operation truncates motion data samples from the motion data associated with an ending position of the diastolic phase that occurs after the select cycle length.

6. The method of claim 4, wherein the motion data defines displacement waveforms in connection with each of the map points, the equalization operation including rotating motion data samples from the motion data to shift the displacement waveforms after a reference point to an end of the cardiac cycle.

7. The method of claim 1, wherein the equalizing operation includes identifying a longest cycle length from the cycle lengths and padding the cycle lengths that are shorter than the longest cycle length by adding pseudo-motion data to the motion data associated with the shorter cycle lengths.

8. The method of claim 1, further comprising:

determining a shortest cycle length associated with cardiac events in the data recordings;

determining a correlation based on mathematical convolution between the shortest cycle length and the motion data from each of the other map points in order to determine a level of similarity in signal morphology of the map points; and

determining a difference between the correlation and a correlation threshold, wherein the equalizing operation is based on the difference between the correlation and the correlation threshold.

9. The method of claim 8,

wherein the equalizing operation comprises performing a compression process to encapsulate an entire behavior of at least one map point of the select number of map points throughout a native cycle length, if the correlation is equal to or more than the correlation threshold, and

wherein the equalizing operation comprises performing at least one of i) a truncation and rotation process;

or iii) an extension and rotation process, if the correlation is less than the correlation threshold.

10. The method of claim 1, further comprising:

determining a shortest cycle length associated with cardiac events during diastole in the data recordings;

determining a longest cycle length associated with cardiac events during diastole in the data recordings;

determining a flatness score (FS) based on the difference between the longest cycle length and the shortest cycle length;

determining whether the FS is larger than a first pre-defined limit, wherein;

if the FS is larger than a first pre-defined limit, the equalizing operation comprises at least performing a compression process, and

if the FS is not larger that the first pre-defined limit, the equalizing operation comprises at least one of i) a truncation and rotation process;

or iii) an extension and rotation process.

11. The method of claim 10, further comprising determining whether the FS is larger than a second pre-defined limit, wherein if the FS is larger than the second pre-defined limit, the equalizing operation comprises performing a combination of truncation and compression.

12. A method to analyze data of a region of interest in order to generate a cardiac map, the method comprising:

utilizing one or more processors;

acquiring data recordings of motion data at each of a select number of map points for the region of interest with a navigation system motion sensor in contact with the region of interest;

determining cycle lengths associated with cardiac events in the data recordings,

equalizing cycle lengths among different map points for the region of interest wherein the equalizing operation generates an equalized motion data set having a common number of motion data samples for each map point;

modifying the motion data based on the equalizing operation; and

displaying the modified motion data on a display.

13. A cardiac mapping system comprising:

a data storage configured to store data recordings of motion data at each of a select number of map points for a region of interest from a motion sensor in contact with the region of interest;

a processor configured to;

determine cycle lengths associated with cardiac events in the data recordings, wherein the processor is configured to determine a plurality of cycle lengths in connection with a first map point of the select number of map points;

equalize cycle lengths among different map points for the region of interest; and

modify the motion data based on the equalizing operation; and

a display configured to communicate the modified motion data to a user.

14. The system of claim 13, wherein the processor is configured to perform at least one of i) a compression process to encapsulate an entire behavior of at least one map point of the select number of map points throughout a native cycle length;

ii) a truncation and rotation process;

or iii) an extension and rotation process.

15. The system of claim 13, wherein the processor is configured to identify a select cycle length from the plurality of cycle lengths and down-sample the motion data for the map points throughout the cycle lengths to produce a down sampled motion data set having a same number of motion data samples for each of the map points.

16. The system of claim 13, wherein the processor is configured to generate an equalized motion data set having a common number of motion data samples for each map point.

17. The system of claim 13, wherein the processor is configured to identify a longest cycle length from the cycle lengths and pad the cycle lengths that are shorter than the longest cycle length by adding pseudo-motion data to the motion data associated with the shorter cycle lengths.

18. A cardiac mapping system comprising:

a data storage configured to store data recordings of motion data at each of a select number of map points for a region of interest from a motion sensor in contact with the region of interest;

a processor configured to;

determine cycle lengths associated with cardiac events in the data recordings;

equalize cycle lengths among different map points for the region of interest, wherein the processor is configured to identify a select cycle length from the cycle lengths and modify the motion data to have a common number of motion data samples for each map point; and

modify the motion data based on the equalizing operation; and

a display configured to communicate the modified motion data to a user.

19. The system of claim 18, wherein the processor truncates motion data samples from the motion data associated with an ending position of the diastolic phase that occurs after the select cycle length.

20. The system of claim 18, wherein the motion data defines displacement waveforms in connection with each of the map points, the processor rotating motion data samples from the motion data to shift the displacement waveforms after a reference point to an end of the cardiac cycle.