Pumping cassette

• US 9,700,660 B2
• Filed: 01/05/2015
• Issued: 07/11/2017
• Est. Priority Date: 02/27/2007
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Dale, James D., Tracey, Brian D., Demers, Jason A., Wilt, Michael J., Grant, Kevin L.
• Primary Examiner(s): Lettman, Bryan
• Application Number:
  US14/589,829
• Publication Number:
  US 20150125319A1
• Time in Patent Office: 918 Days
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1639 linked by membranes
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1664 with temperature control
• CPC Class Codes: A61M 1/1666 by dissolving solids
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/268 the displacement member being flexible, e.g. membranes, diaphragms or bladders
• CPC Class Codes: A61M 60/37 Haemodialysis, haemofiltration or diafiltration
• CPC Class Codes: A61M 60/427 : the force acting on the blood contacting member being hydraulic or pneumatic
• CPC Class Codes: A61M 60/43 : using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/837 : Aspects of flexible displacement members, e.g. shapes or materials
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/849 : Disposable parts
• CPC Class Codes: A61M 60/851 : Valves
• CPC Class Codes: A61M 60/892 : Active valves, i.e. actuated by an external force
• CPC Class Codes: A61M 60/894 : Passive valves, i.e. valves actuated by the blood
• CPC Class Codes: F04B 13/02 : of two or more fluids at the same time
• CPC Class Codes: F04B 23/06 : the pumps being all of reciprocating positive-displacement type
• CPC Class Codes: F04B 41/06 : Combinations of two or more pumps
• CPC Class Codes: F04B 43/00 : Machines, pumps, or pumping installations having flexible working members pumps or pumping installations specially adapted for elastic fluids F04B45/00
• CPC Class Codes: F04B 43/026 : each plate-like pumping flexible member working in its own pumping chamber
• CPC Class Codes: F04B 43/06 : Pumps having fluid drive
• CPC Class Codes: F04B 43/0736 : with two or more pumping chambers in parallel
• CPC Class Codes: F04B 45/02 : having bellows
• CPC Class Codes: F04B 45/0536 : the actuating fluid being controlled by one or more valves
• CPC Class Codes: F04B 49/02 : Stopping, starting, unloading or idling control
• CPC Class Codes: F04B 49/22 : by means of valves F04B49/03 takes precedence
• CPC Class Codes: F04B 53/06 : Venting
• CPC Class Codes: F04B 53/10 : Valves; Arrangement of valves
• CPC Class Codes: F04B 53/16 : Casings; Cylinders; Cylinder liners or heads; Fluid connections
• CPC Class Codes: F04B 7/02 : the valving being fluid-actuated
• CPC Class Codes: F04B 9/109 : having plural pumping chambers
• CPC Class Codes: F17D 3/00 : Arrangements for supervising or controlling working operations
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
• CPC Class Codes: Y10T 137/0324 : With control of flow by a condition or characteristic of a fluid
• CPC Class Codes: Y10T 137/0379 : By fluid pressure
• CPC Class Codes: Y10T 137/2521 : Flow comparison or differential response
• CPC Class Codes: Y10T 137/85978 : With pump
• CPC Class Codes: Y10T 137/86139 : Serial

Abstract

A pumping cassette including a housing having at least two inlet fluid lines and at least two outlet fluid lines. At least one balancing pod within the housing and in fluid connection with the fluid paths. The balancing pod balances the flow of a first fluid and the flow of a second fluid such that the volume of the first fluid equals the volume of the second fluid. The balancing pod also includes a membrane that forms two balancing chambers. Also included in the cassette is at least two reciprocating pressure displacement membrane pumps. The pumps are within the housing and they pump the fluid from a fluid inlet to a fluid outlet line and pump the second fluid from a fluid inlet to a fluid outlet.

Claims

1. A pump cassette comprising a fluid pump, a fluid balancing chamber, a fluid valve and a plurality of fluid flow paths;

the fluid pump comprising a pumping chamber wall separated from a pump actuation chamber wall by a first flexible diaphragm;

the fluid balancing chamber comprising a first chamber wall separated from a second chamber wall by a second flexible diaphragm;

the fluid valve comprising a valve fluid chamber wall separated from a valve actuation chamber wall by a third flexible diaphragm;

the pump cassette comprising a middle plate separating a top plate from a bottom plate;

the top plate comprising the pumping chamber wall, the first chamber wall, the valve fluid chamber wall and the plurality of fluid flow paths;

the bottom plate comprising the pump actuation chamber wall, the second chamber wall and the valve actuation chamber wall;

the middle plate defining a first open region between the pumping chamber wall and pump actuation chamber wall, a second open region between the first chamber wall and second chamber wall, and a third open region between the valve fluid chamber wall and the valve actuation chamber wall, wherein the first, second and third diaphragms are positioned respectively in said first, second and third open regions;

the middle plate enclosing the plurality of fluid flow paths of the top plate;

wherein the pump actuation chamber wall and the valve actuation chamber wall each includes a pneumatic actuation port, and the second chamber wall includes a fluidic port, said fluidic port communicating through the middle plate with one or more of said plurality of fluid flow paths.

2. A pump cassette comprising two fluid pumps, two fluid balancing chambers, a plurality of fluid valves and a plurality of fluid flow paths;

each fluid pump comprising a pumping chamber wall separated from a pump actuation chamber wall by a fluid pump flexible diaphragm;

each fluid balancing chamber comprising a first balancing chamber wall separated from a second balancing chamber wall by a balancing chamber flexible diaphragm;

each of said plurality of fluid valves comprising a valve fluid chamber wall separated from a valve actuation chamber wall by a valve flexible diaphragm;

the pump cassette comprising a middle plate separating a top plate from a bottom plate;

the top plate comprising the pumping chamber wall of each fluid pump, the first balancing chamber wall of each fluid balancing chamber, the valve fluid chamber wall of each of said plurality of fluid valves, and the plurality of fluid flow paths;

the bottom plate comprising the pump actuation chamber wall of each fluid pump, the second balancing chamber wall of each fluid balancing chamber and the valve actuation chamber wall of each of said plurality of fluid valves;

the middle plate defining a pump region between the pumping chamber wall and pump actuation chamber wall of each fluid pump, a balancing chamber region between the first balancing chamber wall and second balancing chamber wall of each fluid balancing chamber, and a valve region between the valve fluid chamber wall and the valve actuation chamber wall of each of said plurality of fluid valves, wherein the fluid pump diaphragm, the balancing chamber diaphragm and the valve diaphragm are positioned respectively in said pump, balancing chamber and valve regions;

the middle plate enclosing the plurality of fluid flow paths of the top plate;

wherein each of the pump actuation chamber walls and each of the valve actuation chamber walls include a pneumatic actuation port, and each of the second balancing chamber walls includes a fluidic port, said fluidic port communicating through the middle plate with one or more of said plurality of fluid flow paths.

3. The pump cassette of claim 2, wherein the plurality of fluid flow paths comprises a first fluid flow path fluidically separate from a second fluid flow path, the first and second fluid flow paths each having separate fluid inlets and fluid outlets on the pump cassette, wherein the fluidic ports of each of the second balancing chamber walls are fluidically connected to the second fluid flow path, and wherein a volume defined by the balancing chamber diaphragm and the first balancing chamber wall of each balancing chamber is fluidically connected to the first fluid flow path.

4. The pump cassette of claim 3, wherein a volume defined by the fluid pump diaphragm and the pumping chamber wall of each fluid pump is fluidically connected to the first fluid flow path.

5. The pump cassette of claim 4, wherein the plurality of fluid valves comprise a pump inlet and pump outlet valve, and a balancing chamber control valve for each of said fluid pumps and fluid balancing chambers in the first fluid flow path.

6. The pump cassette of claim 5, wherein the plurality of fluid valves comprise two balancing chamber control valves for each of said fluid balancing chambers in the second fluid flow path.

7. The pump cassette of claim 3, further comprising a metering pump configured to bypass said fluid pumps and said fluid balancing chambers in the first fluid flow path.

8. The pump cassette of claim 7, wherein the metering pump comprises a metering pumping chamber wall separated from a metering pump actuation chamber wall by a metering pump flexible diaphragm.

9. The pump cassette of claim 8, wherein the top plate comprises the metering pumping chamber wall, the bottom plate comprises the metering pump actuation chamber wall, and the middle plate defines a metering pump region occupied by the metering pump diaphragm.

10. A pump cassette comprising a fluid pump, a fluid balancing chamber, a fluid valve and a plurality of fluid flow paths;

the fluid pump comprising a pumping chamber wall separated from a pump actuation chamber wall by a first region comprising a flexible diaphragm;

the fluid balancing chamber comprising a first chamber wall separated from a second chamber wall by a second region comprising a flexible diaphragm;

the fluid valve comprising a valve fluid chamber wall separated from a valve actuation chamber wall by a third region comprising a flexible diaphragm;

the pump cassette comprising a middle plate separating a top plate from a bottom plate;

the pumping chamber wall, the first chamber wall, the valve fluid chamber wall and the plurality of fluid flow paths being formed in the top plate;

the pump actuation chamber wall, the second chamber wall and the valve actuation chamber wall being formed in the bottom plate;

the middle plate comprising the first region comprising a first flexible diaphragm, the second region comprising a second flexible diaphragm, and the third region comprising a third flexible diaphragm;

the middle plate enclosing the plurality of fluid flow paths formed in the top plate;

wherein pneumatic actuation ports are formed in the pump actuation chamber wall and valve actuation chamber wall of the bottom plate, and a fluidic port is formed in the second chamber wall of the bottom plate, said fluidic port communicating through the middle plate with one or more of said plurality of fluid flow paths.

11. The pump cassette of claim 10, wherein

the first region comprising a flexible diaphragm comprises a first flexible diaphragm,

the second region comprising a flexible diaphragm comprises a second flexible diaphragm, and

the third region comprising a flexible diaphragm comprises a third flexible diaphragm, and wherein

the first region comprising the first flexible diaphragm, the second region comprising the second flexible diaphragm, and the third region comprising the third flexible diaphragm, are defined by, respectively, a first open region between the pumping chamber wall and pump actuation chamber wall, a second open region between the first chamber wall and second chamber wall, and a third open region between the valve fluid chamber wall and the valve actuation chamber wall, wherein the first, second and third diaphragms are positioned respectively in said first, second and third open regions.