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Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)

  • US 9,701,538 B2
  • Filed: 06/02/2014
  • Issued: 07/11/2017
  • Est. Priority Date: 01/28/2008
  • Status: Active Grant
First Claim
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1. A cartridge for the delivery of a therapeutic amount of nitric oxide to a mammal, comprising:

  • a housing including an inner passage and an outer passage forming an annulus with a diameter, wherein the diameter is fixed during the delivery, anda surface active material having a reducing agent located between the inner passage and the outer passage,wherein the housing further includes an inlet and an outlet, wherein the inlet is configured to receive a gas flow including nitrogen dioxide to the inner passage and fluidly communicate the gas flow through the surface active material to the outer passage and finally to the outlet such that the gas flow contacts the reducing agent and the reducing agent converts substantially all of the nitrogen dioxide in the gas flow to nitric oxide,wherein the cartridge comprises three concentric tubes, wherein a space between a first tube and a second tube form the outer passage, a space between the second tube and a third tube form the annulus, and the third tube forms the inner passage, wherein the surface active material is contained within the annulus.

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