Measurement method using oxidase

• US 9,702,844 B2
• Filed: 12/09/2015
• Issued: 07/11/2017
• Est. Priority Date: 10/22/2010
• Status: Active Grant

• Current Assignee: ARKRAY, Inc
• Original Assignee: ARKRAY, Inc
• Inventors: Kaneda, Hisashi
• Primary Examiner(s): NOAKES, SUZANNE MARIE
• Application Number:
  US14/963,363
• Publication Number:
  US 20160091452A1
• Time in Patent Office: 580 Days
• Field of Search: None
• CPC Class Codes: C12Q 1/005 involving specific analytes or enzymes including groups of enzymes, e.g. oxydases; C12Q1/004 takes precedence
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: C12Q 1/26 involving oxidoreductase
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771

Abstract

A method for measuring a target object in a sample by using an oxidase, wherein the influence of dissolved oxygen in the sample can be corrected, is provided. The method comprises: obtaining measurement values by causing the target object in the sample to react with the oxidase under different conditions of two or more types; and performing a correction based on the obtained two or more measurement values and a correction method preliminarily set so as to correct the influence of dissolved oxygen in the sample.

Claims

1. A measurement device comprising:

a sensor section for obtaining measurement information resulting from reactions between a target object in a sample and an oxidase under two or more different types of conditions;

a memory section for storing a correction method, where the correction method corrects for the influence of dissolved oxygen in the sample on the obtained measurement information;

an arithmetic section for selecting the correction method stored in the memory section based on the measurement information obtained by the sensor section, and calculating a corrected value of the measurement information by the correction method;

and a display section for displaying the corrected value.

2. The measurement device according to claim 1, wherein the target object is selected from the group consisting of glucose, lactic acid, bilirubin, cholesterol and ascorbic acid.

3. The measurement device according to claim 1, wherein the target object is glucose.

4. The measurement device according to claim 1, wherein the oxidase is selected from the group consisting of glucose oxidase, lactate oxidase, bilirubin oxidase, cholesterol oxidase, ascorbic acid oxidase, uric acid oxidase, peroxidase, sulfurous acid oxidase, amine oxidase, lysyl oxidase, lysine oxidase, amino acid oxidase, diamine oxidase, pyridoxine phosphate oxidase, protein-lysine 6-oxidase, acyl-CoA oxidase, alcohol oxidase, choline oxidase, pyruvic acid oxidase, sarcosine oxidase, tyramine oxidase and glycerophosphate oxidase.

5. The measurement device according to claim 1, wherein the oxidase is glucose oxidase.