Systems, apparatus and associated methods for needleless delivery of therapeutic fluids

• US 9,706,900 B2
• Filed: 06/17/2013
• Issued: 07/18/2017
• Est. Priority Date: 11/19/2007
• Status: Expired due to Fees

• Current Assignee: Astora Women's Health Holdings LLC (Endo International PLC)
• Original Assignee: Ams Research Corporation (Endo International PLC)
• Inventors: Roychowdhury, Suranjan, Hauschild, Sidney F., Copa, Vincent G.
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): CARPENTER, WILLIAM R
• Application Number:
  US13/919,073
• Publication Number:
  US 20130274703A1
• Time in Patent Office: 1,492 Days
• CPC Class Codes: A61B 1/00006 of control signals
• CPC Class Codes: A61B 1/00011 characterised by signal transmission
• CPC Class Codes: A61B 1/00114 Electrical cables in or with an endoscope
• CPC Class Codes: A61B 1/00124 electrical, e.g. electrical plug-and-socket connection
• CPC Class Codes: A61B 1/015 Control of fluid supply or evacuation
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/6018 providing set-up signals for the apparatus configuration
• CPC Class Codes: A61M 2210/166 Prostate
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Abstract

A needleless fluid delivery system for delivering therapeutic fluids to treatment sites within a patient. The fluid delivery system can include an automated injector source and a needleless access device. The access device can include a delivery scope and a treatment specific applicator. The automated injector source, delivery scope and applicator can be operably coupled with quick-connect style fittings so as to allow for quick replacement and maintenance of used or damaged components. The automated injector source can include a hands-free input mechanism allowing a medical professional to use both hands in manipulating the delivery scope and needleless applicator at the same time an injection is desired. The delivery scope and needleless applicator can comprise flexible or rigid lengths of tubing based on the accessibility of the treatment site. The needleless delivery system can include an imaging system for precisely position the applicator with respect to the treatment location.

Claims

1. A method for delivery a therapeutic fluid to a treatment location comprising:

providing at least one treatment-specific applicator comprising an applicator head having a head delivery lumen and a head vacuum lumen, wherein the at least one treatment-specific applicator is configured for use at a specific treatment location,

providing a flexible scope comprising a scope delivery lumen and a scope vacuum lumen,

advancing the flexible scope through the treatment-specific applicator until the scope delivery lumen is fluidly connected to the head delivery lumen and the scope vacuum lumen is fluidly connected to the head vacuum lumen

accessing a treatment location with the treatment-specific applicator;

connecting the treatment-specific applicator to a connector member of a needleless fluid delivery system including an automated injector such that the automated injector preconfigures a controller for standard operating conditions associated with the treatment-specific applicator;

initiating the scope vacuum lumen and head vacuum lumen to draw tissue at the treatment location to the head delivery lumen, and

delivering a therapeutic fluid from the flexible scope at operating conditions associated with the treatment-specific applicator.

2. The method of claim 1, wherein the automated injector further comprises a touch screen, and delivering a therapeutic fluid comprises interfacing with the touch screen on the automated injector.

3. The method of claim 1, wherein the automated injector further comprises a foot pedal, and delivering a therapeutic fluid comprises stepping on the foot pedal operably connected to the automated injector.

4. The method of claim 1, wherein connecting the treatment-specific applicator to the needleless fluid delivery system, further comprises:

mechanically connecting the at least one treatment-specific applicator to the controller.

5. The method of claim 1, wherein connecting the treatment-specific applicator to the needleless fluid delivery system further comprises:

electronically communicating the at least one treatment-specific applicator to the controller.

6. The method of claim 1, further comprising:

confirming the proximity of the treatment-specific applicator to the treatment location with a medical imaging system.

7. The method of claim 1, wherein the applicator head has an end fire injection lumen, and wherein delivering the therapeutic fluid further comprises administering the therapeutic fluid through the end fire injection lumen.

8. The method of claim 1, wherein the applicator head has a side fire injection lumen, and wherein delivering the therapeutic fluid further comprises administering the therapeutic fluid through the side fire injection lumen.

9. The method of claim 1, wherein the at least one treatment-specific applicator comprises a microchip or a RFID tag capable of communicating with the controller.

10. The method of claim 1, wherein the at least one treatment-specific applicator is configured for treatment locations selected from a rectal treatment location, a gastrointestinal treatment location, a nasal treatment location, a bronchial treatment location, or an esophageal treatment location.