Endoprosthesis for implantation in the heart of a patient

• US 9,707,075 B2
• Filed: 01/14/2016
• Issued: 07/18/2017
• Est. Priority Date: 02/26/2008
• Status: Active Grant

• Current Assignee: JenaValve Technology, Inc.
• Original Assignee: JenaValve Technology, Inc.
• Inventors: Straubinger, Helmut, Jung, Johannes
• Primary Examiner(s): SCHALL, MATTHEW WAYNE
• Application Number:
  US14/995,484
• Publication Number:
  US 20160220364A1
• Time in Patent Office: 551 Days
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/844 folded prior to deployment
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0023 triangular

Abstract

The present invention relates to a stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch via a first connecting web. The stent moreover comprises at least one auxiliary retaining arch which connects the respective arms of the at least one retaining arch connected to the at least one positioning arch.

Claims

1. An endoprosthesis, comprising:

a stent comprising;

an annular skirt portion comprising a plurality of closed cells extending around a circumference of the stent and disposed at a first end of the stent;

a plurality of first arches each having an apex pointing toward the first end of the stent, the plurality of first arches configured to be disposed within sinus pockets of a native valve radially outward of leaflets of the native valve;

a plurality of arms each having a first end joined to a first end of an adjacent arm and a second end joined to the annular skirt portion, each first arch being positioned between two arms of the plurality of arms, and the plurality of arms being configured to be disposed radially inward of the leaflets of the native valve; and

a plurality of second arches each having an apex pointing toward a second end of the stent, each apex of a second arch of the plurality of arches being axially aligned, along a longitudinal direction of the stent, with an apex of a corresponding first arch of the plurality of first arches; and

a heart valve prosthesis attached to the stent.

2. The endoprosthesis of claim 1, wherein the stent comprises a plurality of commissure posts to which the heart valve prosthesis is attached.

3. The endoprosthesis of claim 2, wherein the stent includes exactly three commissure posts each comprising one or more suture holes for securing the heart valve prosthesis thereto.

4. The endoprosthesis of claim 1, wherein the apex of each first arch of the plurality of first arches is between two arms of the plurality of arms.

5. The endoprosthesis of claim 1, wherein each first arch is joined to a corresponding second arch to define a closed cell between the apex of the first arch and the apex of the corresponding second arch.

6. The endoprosthesis of claim 1, wherein the annular skirt portion flares radially outward relative to a second end of the stent opposite the first end of the stent.

7. The endoprosthesis of claim 1, wherein the heart valve prosthesis comprises three leaflets.

8. The endoprosthesis of claim 1, wherein at least a portion of the stent proximate the first end of the stent is covered by a pericardial material.

9. The endoprosthesis of claim 2, wherein a distalmost end of each commissure post defines a second end of the stent.

10. An endoprosthesis, comprising:

a stent comprising;

an annular skirt portion comprising a plurality of closed cells extending around a circumference of the stent and disposed at a first end of the stent;

a plurality of first arches each having an apex pointing toward the first end of the stent, the plurality of first arches configured to be disposed within respective sinus pockets of a native valve radially outward of leaflets of the native valve;

a plurality of arms each having a first end joined to a first end of an adjacent arm and a second end joined to the annular skirt portion, each first arch being positioned between two arms of the plurality of arms, and the plurality of arms being configured to be disposed radially inward of the leaflets of the native valve;

a plurality of second arches each having an apex pointing toward a second end of the stent, the plurality of second arches being joined to the plurality of first arches; and

a plurality of commissure posts; and

a heart valve prosthesis attached to the plurality of commissure posts.

11. The endoprosthesis of claim 10, wherein each commissure post of the plurality of commissure posts includes one or more suture holes to which the heart valve prosthesis is attached.

12. The endoprosthesis of claim 10, wherein the annular skirt portion flares radially outward relative to a second end of the stent opposite the first end of the stent.

13. The endoprosthesis of claim 10, wherein stent is self-expandable.

14. The endoprosthesis of claim 10, wherein the stent is cut from a single piece of metal, such that the annular portion, the plurality of first arches, the plurality of arms, and the plurality of second arches are integral with one another.

15. The endoprosthesis of claim 10, wherein each first arch is joined to a corresponding second arch.

16. An endoprosthesis, comprising:

a stent comprising;

an annular skirt portion comprising a plurality of closed cells extending around a circumference of the stent and disposed at a first end of the stent;

a plurality of first arches each having an apex pointing toward the first end of the stent, the plurality of first arches configured to be disposed within respective sinus pockets of a native valve radially outward of leaflets of the native valve;

a plurality of arms each having a first end joined to a first end of an adjacent arm and a second end joined to the annular skirt portion, the plurality of arms being configured to be disposed radially inward of the leaflets of the native valve; and

a plurality of second arches each having an apex pointing toward a second end of the stent, each first arch being joined to a corresponding second arch to define a closed cell between the apex of the first arch and the apex of the corresponding second arch; and

a heart valve prosthesis attached to the stent.

17. The endoprosthesis of claim 16, wherein the annular portion, the plurality of first arches, the plurality of arms, and the plurality of second arches of the stent are integral with one another.

18. The endoprosthesis of claim 16, wherein the stent comprises a plurality of commissure posts each defining one or more suture holes to which the heart valve prosthesis is attached.

19. The endoprosthesis of claim 16, wherein the apex of each first arch is between two arms of the plurality of arms.

20. The endoprosthesis of claim 18, wherein a distalmost end of each commissure post includes a feature configured to engage and selectively retain the stent to a catheter.