Ablation system, methods, and controllers

• US 9,713,490 B2
• Filed: 03/11/2014
• Issued: 07/25/2017
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Inventors: Brotz, Joseph Allen, Hein, John Eric, Froehlich, Raymond Vincent, Barnier, Joseph William
• Primary Examiner(s): FOWLER, DANIEL WAYNE
• Application Number:
  US14/204,193
• Publication Number:
  US 20140276773A1
• Time in Patent Office: 1,232 Days
• CPC Class Codes: A61B 18/12 by passing a current through the tissue to be heated, e.g. high-frequency current
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00267 having a basket shaped structure
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00654 with individual control of each of a plurality of energy emitting elements
• CPC Class Codes: A61B 2018/00666 using a threshold value
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00714 Temperature
• CPC Class Codes: A61B 2018/00779 Power or energy
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00892 Voltage
• CPC Class Codes: A61B 2018/00898 Alarms or notifications created in response to an abnormal condition
• CPC Class Codes: A61B 2018/00988 Means for storing information, e.g. calibration constants, or for preventing excessive use, e.g. usage, service life counter
• CPC Class Codes: H03L 7/091 the phase or frequency detector using a sampling device H03L7/087 takes precedence
• CPC Class Codes: H04L 7/06 the synchronisation signals differing from the information signals in amplitude, polarity or frequency or length

Abstract

In a multi-electrode ablation system, method, and controller, the controller is configured to measure a first current through a common return path when a first voltage is applied by a power supply to a first electrode of a plurality of electrodes, measure a second current through the common return path when a second voltage is applied by the power supply to a second electrode of the plurality of electrodes, measure a third current through the common return path when a third voltage is applied by the power supply concurrently to the first electrode and the second electrode, and determine a common path impedance based at least in part on the first voltage and the first current, the second voltage and the second current, and the third voltage and the third current.

Claims

1. A method of determining a common path impedance in a multi-electrode ablation system using a single current sensor in a common return path, said method comprising:

measuring, during a measurement period, a first current through a common return path for the system when a first voltage is applied to a first electrode;

measuring, during the measurement period, a second current through the common return path when a second voltage is applied to a second electrode;

measuring, during the measurement period, a third current through the common return path when a third voltage is applied concurrently to the first electrode and the second electrode;

determining a common path impedance based at least in part on the first voltage and the first current, the second voltage and the second current, and the third voltage and the third current;

determining a therapeutic impedance for the first electrode by subtracting the common path impedance from a first branch resistance for the first electrode;

determining a therapeutic impedance for the second electrode by subtracting the common path impedance from a second branch resistance for the second electrode;

determining, after the measurement period, based on the first electrode therapeutic impedance and the second electrode therapeutic impedance, an amount of energy dissipated through each of the first and second electrodes during the measurement period; and

calculating, based on the amount of energy dissipated through each of the first and second electrodes during the measurement period, a remaining on time for each of the first and second electrodes, wherein the remaining on time is an amount of time that the associated electrode should be activated during an output period that follows the measurement period in order for the associated electrode to dissipate a predetermined total amount of energy over the measurement period and the output period.

2. The method set forth in claim 1 wherein the first voltage, the second voltage, and the third voltage are substantially equal.

3. The method set forth in claim 1 further comprising:

coupling the first voltage to the first electrode with the second voltage decoupled from the second electrode;

coupling the second voltage to the second electrode with the first voltage decoupled from the first electrode; and

coupling the third voltage concurrently to the first electrode and the second electrode.

4. The method set forth in claim 1 further comprising:

determining, based on the first electrode therapeutic impedance and the second electrode therapeutic impedance, a remaining amount of energy to be dissipated through each of the first and second electrodes during the output period.

5. The method set forth in claim 1 wherein determining a common path impedance includes determining the first branch resistance based on the first voltage and the first current, determining the second branch resistance based on the second voltage and the second current, and determining a combination branch resistance based on the third voltage and the third current.

14. The method set forth in claim 1 further comprising deactivating the first and second electrodes when the respective remaining on times for the first and second electrodes are reached.

6. A multi-electrode ablation system comprising:

a power supply configured to be coupled to a plurality of electrodes by a common return path; and

a controller configured to;

measure, during a measurement period, a first current through the common return path when a first voltage is applied by the power supply to a first electrode of the plurality of electrodes;

measure, during the measurement period, a second current through the common return path when a second voltage is applied by the power supply to a second electrode of the plurality of electrodes;

measure, during the measurement period, a third current through the common return path when a third voltage is applied by the power supply concurrently to the first electrode and the second electrode;

determine a common path impedance based at least in part on the first voltage and the first current, the second voltage and the second current, and the third voltage and the third current;

determine a therapeutic impedance for the first electrode by subtracting the common path impedance from a first branch resistance for the first electrode;

determine a therapeutic impedance for the second electrode by subtracting the common path impedance from a second branch resistance for the second electrode; and

determine, after the measurement period, based on the first electrode therapeutic impedance and the second electrode therapeutic impedance, an amount of energy dissipated through each of the first and second electrodes during the measurement period; and

calculate, based on the amount of energy dissipated through each of the first and second electrodes during the measurement period, a remaining on time for each of the first and second electrodes, wherein the remaining on time is an amount of time that the associated electrode should be activated during an output period that follows the measurement period in order for the associated electrode to dissipate a predetermined total amount of energy over the measurement period and the output period.

7. The system set forth in claim 6 wherein the first voltage, the second voltage, and the third voltage are substantially equal.

8. The system set forth in claim 6 further comprising a current sensor communicatively coupled to the controller and configured to detect current through the common return path.

9. The system set forth in claim 6 wherein the controller is further configured to couple voltage from the power supply to the plurality of electrodes based at least in part on the determined common path impedance.

10. The system set forth in claim 6 wherein the controller is further configured to determine, based on the first electrode therapeutic impedance and the second electrode therapeutic impedance, a remaining amount of energy to be dissipated through each of the first and second electrodes during the output period.

15. The system set forth in claim 6 wherein the controller is further configured to deactivate the first and second electrodes when the respective remaining on times for the first and second electrodes are reached.

11. A controller for a multi-electrode ablation system including a plurality of electrodes and a power supply, the plurality of electrodes coupled to the power supply by a common return path, the controller comprising:

a processor; and

a memory device, the memory device including instructions that, when executed by the processor, cause the processor to;

measure, during a measurement period, a first current through the common return path when a first voltage is applied to a first electrode of the plurality of electrodes;

measure, during the measurement period, a second current through the common return path when a second voltage is applied to a second electrode of the plurality of electrodes;

measure, during the measurement period, a third current through the common return path when a third voltage is applied concurrently to the first electrode and the second electrode;

determine a common path impedance based on the first voltage and the first current, the second voltage and the second current, and the third voltage and the third current;

determine a therapeutic impedance for the first electrode by subtracting the common path impedance from a first branch resistance for the first electrode;

determine a therapeutic impedance for the second electrode by subtracting the common path impedance from a second branch resistance for the second electrode;

determine, after the measurement period, based on the first electrode therapeutic impedance and the second electrode therapeutic impedance, an amount of energy dissipated through each of the first and second electrodes during the measurement period; and

calculate, based on the amount of energy dissipated through each of the first and second electrodes during the measurement period, a remaining on time for each of the first and second electrodes, wherein the remaining on time is an amount of time that the associated electrode should be activated during an output period that follows the measurement period in order for the associated electrode to dissipate a predetermined total amount of energy over the measurement period and the output period.

12. The controller set forth in claim 11 wherein the memory device further includes instructions that, when executed by the processor, cause the processor to couple voltage from a power supply to the plurality of electrodes based at least in part on the determined common path impedance.

13. The controller set forth in claim 11 wherein the memory device further includes instructions that, when executed by the processor, cause the processor to determine, based on the first electrode therapeutic impedance and the second electrode therapeutic impedance, a remaining amount of energy to be dissipated through each of the first and second electrodes during the output period.

16. The controller set forth in claim 11 wherein the memory device further includes instructions that, when executed by the processor, cause the processor to deactivate the first and second electrodes when the respective remaining on times for the first and second electrodes are reached.