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Method for modifying food intake and regulating food preference with a DPP-4 inhibitor

  • US 9,713,618 B2
  • Filed: 05/21/2013
  • Issued: 07/25/2017
  • Est. Priority Date: 05/24/2012
  • Status: Active Grant
First Claim
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1. A method of shifting food or taste preference or choice of a subject in need thereof away from an unhealthy food toward a healthy food, the method comprising administering to the subject an effective amount of a dipeptidyl peptidase-4 (DPP-4) inhibitor in combination with a glucagon-like peptide-1 (GLP-1) receptor agonist which is exenatide or human GLP-1, wherein the unhealthy food is a food having a high glycemic index and/or wherein mono- and/or di-saccharides constitute a large proportion of the total amount of carbohydrates and/or wherein a large proportion of the total amount of energy stems from fat, and wherein the healthy food is a food having a low glycemic index and/or wherein mono- and/or di-saccharides constitute a small proportion of the total amount of carbohydrates and/or wherein a small proportion of the total amount of energy stems from fat, wherein the DPP-4 inhibitor is administered subcutaneously.

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