Foamable carriers
First Claim
Patent Images
1. A composition comprising a foamable composition and a liquefied or compressed gas propellant, the foamable composition comprising:
- i) a surface-active agent;
ii) about 2% to about 75% by weight of the foamable composition of an organic solvent selected from the group consisting of an emollient, a polar solvent, an oil, and a mixture of any two or more thereof;
iii) a stabilizer comprising about 0.01% to about 5% by weight of the foamable composition of at least one polymeric agent and about 0.1% to about 5% by weight of the foamable composition of at least one foam adjuvant;
iv) water; and
v) an active agent selected from the group consisting of an anti-parasitic agent, an antifungal agent, an antiviral agent, a corticosteroid, an anticancer agent, an estrogen, and a mixture of any two or more thereof;
wherein the combined amount of the foam adjuvant, surface active agent, and poymeric agent is less than about 8% by weight of the foamable composition;
wherein upon release from a foam dispenser, a foam is produced; and
wherein the foam remains stable as a foam for at east 60 seconds at 37°
C.
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Accused Products
Abstract
The invention relates to an alcohol-free cosmetic or therapeutic foam carrier comprising water, a hydrophobic organic carrier, a foam adjuvant agent, a surface-active agent and a gelling agent. The cosmetic or therapeutic foam carrier does not contain aliphatic alcohols, making it non-irritating and non-drying. The alcohol-free foam carrier is suitable for inclusion of both water-soluble and oil soluble therapeutic and cosmetic agents.
977 Citations
52 Claims
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1. A composition comprising a foamable composition and a liquefied or compressed gas propellant, the foamable composition comprising:
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i) a surface-active agent; ii) about 2% to about 75% by weight of the foamable composition of an organic solvent selected from the group consisting of an emollient, a polar solvent, an oil, and a mixture of any two or more thereof; iii) a stabilizer comprising about 0.01% to about 5% by weight of the foamable composition of at least one polymeric agent and about 0.1% to about 5% by weight of the foamable composition of at least one foam adjuvant; iv) water; and v) an active agent selected from the group consisting of an anti-parasitic agent, an antifungal agent, an antiviral agent, a corticosteroid, an anticancer agent, an estrogen, and a mixture of any two or more thereof; wherein the combined amount of the foam adjuvant, surface active agent, and poymeric agent is less than about 8% by weight of the foamable composition; wherein upon release from a foam dispenser, a foam is produced; and wherein the foam remains stable as a foam for at east 60 seconds at 37°
C.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A composition comprising a foamable composition and a liquefied or compressed gas propellant, the foamable composition comprising:
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i) a surface-active agent; ii) about 70% to about 99% by weight of the foamable composition of a hydrophobic organic solvent; iii) a stabilizer selected from the group consisting of about 0.01% to about 5% by weight of the foamable composition of a polymeric agent and about 0.1% to about 5% by weight of the foamable composition of a foam adjuvant; wherein upon release from a foam dispenser, a foam is produced; and wherein the foam remains stable as a foam for at least 60 seconds at 37°
C.- View Dependent Claims (42, 43, 44, 45, 46)
and wherein the antiinfiammatory agent is selected from the group consisting of phenylbutazone, oxyphenbutazone, feprazone, azapropazone, trimethazone, and a mixture of any two or more thereof.
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47. A composition comprising, an active agent, a foamable composition, and a liquefied or compressed gas propellant, the foamable composition comprising:
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i) about 2% to about 75% by weight of the foamable composition of an organic solvent selected from the group consisting of an emollient, a polar solvent, an oil, and a mixture thereof; ii) a stabilizer selected from the group consisting of about 0.01% to about 5% by weight of the foamable composition of at least one polymeric agent, about 0.1% to about 5% by weight of the foamable composition of at least one foam adjuvant, and a mixture thereof; iii) water; iv) an active agent selected from the group consisting of an anti-parasitic agent, an antifungal agent, an antiviral agent, a corticosteroid, an anticancer agent, an estrogen, and a mixture of any two or more thereof; and v) optionally, a surfactant; wherein the combined amount of the foam adjuvant, polymeric agent, and surface active agent, if present, is less than about 8% by weight of the foamable composition; wherein upon release from a foam dispenser, a foam is produced; and wherein the foam remains stable as a foam for at least 60 seconds at 37°
C. - View Dependent Claims (48)
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49. A composition comprising an active agent, a foamable composition and a liquefied or compressed gas propellant, the foamable composition comprising:
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i) about 0.1% to about 5% by weight of the foamable composition of a surface-active agent; ii) about 2% to about 75% by weight of the foamable composition of an organic solvent selected from the group consisting of an emollient, a polar solvent, an oil, and a mixture thereof; iii) a stabilizer selected from the group consisting of about 0.01 % to about 5% by weight of the foamable composition of at least one film forming or mucoadhesive agent, at least one foam adjuvant, and a mixture thereof; iv) water; and v) an active agent selected from the group consisting of an anti-parasitic agent, an antifungal agent, an antiviral agent, a corticosteroid, an anticancer agent, an estrogen, and a mixture of any two or more thereof; wherein the surface-active agent is selected from the group consisting of a non ionic surface-active agent, an amphoteric surface-active agent, and a mixture thereof; wherein the combined amount of the foam adjuvant, surface active agent, and polymeric agent is less than about 8% by weight of the foamable composition; wherein upon release from a foam dispenser, a foam is produced; and wherein the foam remains stable as a foam for at least 60 seconds at 37°
C.- View Dependent Claims (50, 51, 52)
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Specification