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Mesh implant for use in reconstruction of soft tissue defects

  • US 9,717,825 B2
  • Filed: 04/07/2011
  • Issued: 08/01/2017
  • Est. Priority Date: 12/23/2004
  • Status: Active Grant
First Claim
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1. An at least partially resorbable mesh implant for use in reconstruction of soft tissue defects, wherein the mesh implant comprises:

  • a first material in a first arrangement of multifilaments;

    a second material in a second arrangement of multifilaments, wherein the second material is substantially degraded at a later point in time in a body than the first material and wherein the first arrangement and the second arrangement are in different patterns; and

    wherein individual filaments of a multifilament of the first arrangement are in directly spun form and are not twisted relative to one another and the multifilament comprises interstices between the individual filaments prior to any degradation and prior to beginning implantation that create a capillary effect for blood within the body such that fibroblasts and macrophages are present in the interstices,wherein individual filaments of a multifilament of the second arrangement are in directly spun form and are not twisted relative to one another and the multifilament comprises interstices between the individual filaments prior to any degradation and prior to beginning implantation that create a capillary effect for blood within the body such that fibroblasts and macrophages are present in the interstices,wherein the first material is made from a copolymer composed of at least 80 weight-% glycolide monomer or para-dioxanone monomer,wherein the first material comprises a multifilament with 5 to 15 individual filaments and the multifilament has a linear density in the range of 60 denier to 240 denier,wherein the second material is made from a copolymer composed of at least 80 weight-% L-lactide monomer, andwherein the second material comprises a multifilament with 60 to 100 individual filaments and the multifilament has a linear density in the range of 120 to 280 denier.

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