Substituted pyridines as sodium channel blockers
1 Assignment
0 Petitions
Accused Products
Abstract
The invention relates to substituted pyridine and pyrimidine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1, R2a, R2b, A1, A2, X, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
88 Citations
20 Claims
- 1. A compound having Formula I:
Specification