Microscopy imaging
First Claim
Patent Images
1. An apparatus comprising:
- an imaging device having;
a light source;
a photosensitive array of pixels,a first surface configured to be movable to and removable from a predefined position relative to the photosensitive array of pixels,a mechanism configured to enable the first surface to remain at the predefined position after the first surface has been moved to the predefined position and before it is removed from the predetermined position, anda second surface associated with the array and configured to receive a specimen with at least a part of the specimen within a specimen chamber defined at least in part by the first surface and the second surface and at a distance from a surface of the photosensitive array equivalent to less than ten times the average wavelength produced by the light source when the first surface is in the predefined position.
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Abstract
Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
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Citations
94 Claims
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1. An apparatus comprising:
an imaging device having; a light source; a photosensitive array of pixels, a first surface configured to be movable to and removable from a predefined position relative to the photosensitive array of pixels, a mechanism configured to enable the first surface to remain at the predefined position after the first surface has been moved to the predefined position and before it is removed from the predetermined position, and a second surface associated with the array and configured to receive a specimen with at least a part of the specimen within a specimen chamber defined at least in part by the first surface and the second surface and at a distance from a surface of the photosensitive array equivalent to less than ten times the average wavelength produced by the light source when the first surface is in the predefined position. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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49. An apparatus comprising:
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an imaging device having a photosensitive array, a first surface configured to be movable to and removable from a predefined position relative to the photosensitive array of pixels, a mechanism configured to enable the first surface to remain at the predefined position after the first surface has been moved to the predefined position and before it is removed from the predetermined position, and a second surface associated with the array and configured to receive a specimen with at least a part of the specimen within a specimen chamber defined at least in part by the first surface and the second surface and at a distance from the photosensitive array that satisfies or at least approximately satisfies a near-field criterion based on the movement of the first surface toward the predefined position. - View Dependent Claims (50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79)
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80. A method comprising
receiving light from a light source at a second surface associated with a photosensitive array of pixels; -
moving a first surface toward a predefined position relative to the second surface such that when the first surface is in the predefined position, at least a part of a specimen within a specimen chamber defined at least in part by the first surface and the second surface is at a distance from the second surface associated with the photosensitive array that is equivalent to less than ten times the average wavelength produced by the light source, enabling the first surface to remain at the predefined position after the first surface has been moved to the predefined position and before it is removed from the predetermined position, using signals generated by the photosensitive array to produce a high resolution image of the specimen, and removing the first surface from the predefined position. - View Dependent Claims (81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94)
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Specification