Analyte monitoring device and methods

• US 9,724,029 B2
• Filed: 02/23/2015
• Issued: 08/08/2017
• Est. Priority Date: 02/26/2009
• Status: Expired due to Fees

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Rush, Benjamin M., Hoss, Udo, Feldman, Benjamin J., Liu, Zenghe, Cho, Hyun
• Primary Examiner(s): Natnithithadha, Navin
• Application Number:
  US14/629,171
• Publication Number:
  US 20150173657A1
• Time in Patent Office: 897 Days
• Field of Search: 600309, 600345-366
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 2560/0443 Modular apparatus
• CPC Class Codes: A61B 5/1451 for interstitial fluid
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/7405 using sound
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/7455 characterised by tactile indication, e.g. vibration or electrical stimulation

Abstract

Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts, on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes, on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided.

Claims

1. A system for determining analyte concentration, comprising:

an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer;

an on-body electronics unit including a housing having a plurality of electrical contacts concentrically positioned on the on-body electronics housing, the on-body electronics unit coupled to the analyte sensor, comprising a first and second resistor-capacitor (RC) pair in series and electrically coupled to the analyte sensor such that a first voltage across the first RC pair represents a real-time current analyte concentration level, a second voltage across the second RC pair represents an average analyte concentration level over a period of time, and a difference between the first and second voltages represents a real-time trending of the analyte concentration level; and

a data analysis unit in communication with the on body electronics unit.

2. The system of claim 1, wherein the analyte sensor is a self powered sensor.

3. The system of claim 1, wherein the analyte sensor is a glucose sensor.

4. The system of claim 1, wherein data analysis unit comprises a housing comprising a plurality of probes provided on the data analysis unit housing, each of the plurality of probes on the data analysis unit housing configured to electrically couple to the respective one of the plurality of the electrical contacts on the on-body electronics housing when the data analysis unit is positioned in physical contact with the on-body electronics.

5. The system of claim 1, wherein each of the plurality of electrical contacts on the on-body electronics housing are spaced apart by a predetermined distance relative to each other.

6. The system of claim 1, wherein the data analysis unit includes one of a reader or a blood glucose meter.

7. The system of claim 1, wherein the data analysis unit includes an output unit to output one or more indications related to the one or more of the substantially real time monitored analyte concentration level, the monitored analyte concentration level over a predetermined time period, the rate of change of the monitored analyte concentration level, or one or more combinations thereof.

8. The system of claim 7, wherein the output unit includes one or more of a visual output unit, an audible output unit, or a vibratory output unit.

9. The system of claim 1, wherein the predetermined time period includes about three hours.

10. The system of claim 1, wherein the on-body electronics includes one or more data processing components to one or more filter, encode, store, analyze the one or more signals from the analyte sensor.

11. The system of claim 10, wherein the one or more data processing components determines a three hour trend information based on analyte concentration monitored by the analyte sensor.

12. The system of claim 1, wherein the data analysis unit calculates the difference between the first voltage and the second voltage to determine the real-time trending of the analyte concentration level.

13. The system of claim 1, wherein the data analysis unit includes an output unit that outputs a first indication of the real-time current analyte concentration level and a second indication of the real-time trending of the analyte concentration level.

14. The system of claim 1, wherein one or more signals on the plurality of probes on the data analysis unit housing comprises the first voltage and the second voltage and corresponds to one or more of a substantially real time monitored analyte concentration level, monitored analyte concentration level over a predetermined time period, or a rate of change of the monitored analyte concentration level, or one or more combinations thereof.