Physiological measurement using wearable device
First Claim
1. A wearable device, comprising:
- a mount for mounting the wearable device to an external surface of a body proximate to a portion of subsurface vasculature;
a magnet;
a detector;
a communication interface;
a processor;
a non-transitory computer-readable medium; and
program instructions stored in the non-transitory computer-readable medium, wherein the program instructions are executable by the processor to cause the wearable device to perform functions comprising;
operating the magnet to direct a magnetic field into the portion of subsurface vasculature, wherein the magnetic field causes functionalized magnetic nanoparticles that have been introduced into the body to collect in a lumen of the portion of subsurface vasculature, wherein the functionalized magnetic nanoparticles each comprise an antibody and a marker, wherein the marker is a fluorophore, an autofluorescent marker, a luminescent marker, or a chemo-luminescent marker, and wherein the marker produces fluorescence radiation indicative of an analyte;
operating the detector to detect the fluorescence radiation produced by the marker in the functionalized magnetic nanoparticles collected in the lumen of the subsurface vasculature by the magnetic field;
using the fluorescence radiation detected by the detector to detect a presence of the analyte;
determining whether the presence of the analyte indicates a medical condition; and
in response to a determination that the medical condition is indicated, transmitting data representative of the medical condition via the communication interface.
4 Assignments
0 Petitions
Accused Products
Abstract
A wearable device includes a detector configured to detect a response signal transmitted from a portion of subsurface vasculature, the response signal being related to binding of a clinically-relevant analyte to functionalized particles present in a lumen of the subsurface vasculature. Program instructions stored in a computer readable medium of the device, and executable by a processor, may cause the device to determine a concentration of the clinically-relevant analyte based on the response signal detected by the detector; determine whether a medical condition is indicated based on at least the concentration of the clinically-relevant analyte; and, in response to a determination that the medical condition is indicated, transmit data representative of the medical condition via the communication interface. The device may also include a signal source configured to transmit an interrogating signal into the portion of subsurface vasculature, thereby generating a response signal in response to the interrogating signal.
32 Citations
14 Claims
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1. A wearable device, comprising:
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a mount for mounting the wearable device to an external surface of a body proximate to a portion of subsurface vasculature; a magnet; a detector; a communication interface; a processor; a non-transitory computer-readable medium; and program instructions stored in the non-transitory computer-readable medium, wherein the program instructions are executable by the processor to cause the wearable device to perform functions comprising; operating the magnet to direct a magnetic field into the portion of subsurface vasculature, wherein the magnetic field causes functionalized magnetic nanoparticles that have been introduced into the body to collect in a lumen of the portion of subsurface vasculature, wherein the functionalized magnetic nanoparticles each comprise an antibody and a marker, wherein the marker is a fluorophore, an autofluorescent marker, a luminescent marker, or a chemo-luminescent marker, and wherein the marker produces fluorescence radiation indicative of an analyte; operating the detector to detect the fluorescence radiation produced by the marker in the functionalized magnetic nanoparticles collected in the lumen of the subsurface vasculature by the magnetic field; using the fluorescence radiation detected by the detector to detect a presence of the analyte; determining whether the presence of the analyte indicates a medical condition; and in response to a determination that the medical condition is indicated, transmitting data representative of the medical condition via the communication interface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification