Bone graft injection methods

• US 9,730,773 B2
• Filed: 05/08/2015
• Issued: 08/15/2017
• Est. Priority Date: 04/22/2015
• Status: Active Grant

• Current Assignee: Maxillent Ltd.
• Original Assignee: Maxillent Ltd.
• Inventors: Uchitel, Ilan, Alphandary, Adi, Fostick, Gideon, Gross, Yossi, Sohn, Zev
• Primary Examiner(s): Coley, Zade
• Application Number:
  US14/707,688
• Publication Number:
  US 20160310192A1
• Time in Patent Office: 830 Days
• CPC Class Codes: A61B 17/8808 with sealing collar for bone cavity
• CPC Class Codes: A61B 17/8811 characterised by the introducer tip, i.e. the part inserted into or onto the bone
• CPC Class Codes: A61B 17/8816 characterised by the conduit, e.g. tube, along which fluid flows into the body or by conduit connections
• CPC Class Codes: A61B 17/8822 characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum
• CPC Class Codes: A61B 17/8827 with filtering, degassing, venting or pressure relief means
• CPC Class Codes: A61B 2017/00539 hydraulically
• CPC Class Codes: A61B 2017/00734 battery operated
• CPC Class Codes: A61B 2017/8813 Discharging means for excessively introduced fluid fillers, e.g. discharging excess cement
• CPC Class Codes: A61B 2017/8838 for mixing bone cement or fluid fillers
• CPC Class Codes: A61B 2090/036 abutting on tissue or skin
• CPC Class Codes: A61C 1/0084 Supply units, e.g. reservoir arrangements, specially adapted pumps
• CPC Class Codes: A61C 1/0092 Pumps specially adapted therefor
• CPC Class Codes: A61C 1/06 with electric drive
• CPC Class Codes: A61C 1/087 Supplying powder or medicines
• CPC Class Codes: A61C 17/0202 Hand-pieces
• CPC Class Codes: A61C 17/14 Dental appliances for receiving spittle, with or without rinsing means therefor, e.g. dental basins, spittoons, cuspidors
• CPC Class Codes: A61C 3/02 Tooth drilling or cutting instruments; Instruments acting like a sandblast machine
• CPC Class Codes: A61C 8/0006 Periodontal tissue or bone regeneration support means for endoprosthetic bone substitute or bone graft implants A61F2/2846
• CPC Class Codes: A61C 8/0092 for sinus lifting

Abstract

A method is provided that includes injecting, from a first side of a bone, through (a) exactly one bore that passes through the bone from the first side to a second side of the bone, and (b) into a cavity adjacent to the second side of the bone, a solid-liquid composition of solid particles and a physiological liquid solution. The physiological liquid solution is drained from the cavity and through the bore while passage of the solid particles of the solid-liquid composition is inhibited, such that the solid particles accumulate in the cavity.

Claims

1. A method comprising:

injecting, during a dental procedure, from a first side of a bone, through (a) exactly one bore that passes through the bone from the first side to a second side of the bone, and (b) into a cavity adjacent to the second side of the bone, a solid-liquid composition of solid particles and a physiological liquid solution; and

draining, during the dental procedure, the physiological liquid solution from the cavity and through the bore while inhibiting passage of the solid particles of the solid-liquid composition, such that the solid particles accumulate in the cavity,

wherein injecting the solid-liquid composition comprises pumping the solid-liquid composition at a pulsating hydraulic pressure that periodically varies between positive and negative.

2. The method according to claim 1, wherein inhibiting the passage of the solid particles comprises using a filter to inhibit the passage of the solid particles.

3. The method according to claim 2, wherein injecting the solid-liquid composition comprises injecting the solid-liquid composition such that at least 50% of the physiological liquid solution drains through the filter in a distal-to-proximal direction.

4. The method according to claim 1, wherein injecting the solid-liquid composition comprises injecting 2-300 ml of the solid-liquid composition.

5. The method according to claim 1, wherein the cavity is between the second side of the bone and a membrane.

6. The method according to claim 5, further comprising, before injecting the solid-liquid composition, raising the membrane to form the cavity between the second side of the bone and the membrane.

7. The method according to claim 5, wherein the membrane is a Schneiderian membrane.

8. The method according to claim 1, further comprising, after injecting the solid-liquid composition, implanting an implant at least partially within the cavity.

9. The method according to claim 1, wherein the solid particles are solid bone graft particles, and wherein injecting comprises injecting the solid-liquid composition of the solid bone graft particles and the physiological liquid solution.

10. The method according to claim 1, wherein draining the physiological liquid solution comprises suctioning the physiological liquid solution at a negative hydraulic pressure.

11. The method according to claim 1, wherein injecting the solid-liquid composition comprises activating a combining unit to provide the solid-liquid composition by combining the solid particles with the physiological liquid solution.

12. The method according to claim 11, wherein the combining unit comprises a mixing unit, and wherein activating the combining unit comprises activating the mixing unit to provide the solid-liquid composition by mixing the solid particles with the physiological liquid solution.

13. The method according to claim 1, wherein the solid particles are selected from the group consisting of:

drug-releasing solid particles and solid drug particles, and wherein injecting comprises injecting the solid-liquid composition of the selected solid particles and the physiological liquid solution.