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Method and system for treating cancer cachexia

  • US 9,730,967 B2
  • Filed: 02/21/2017
  • Issued: 08/15/2017
  • Est. Priority Date: 02/04/2011
  • Status: Active Grant
First Claim
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1. A method of treating cancer cachexia in a subject in need of such treatment, said method comprising a step of administering a therapeutically effective amount of a composition comprising bacillus calmette-guerin adapted to produce tomatidine, wherein the cancer is bladder cancer;

  • andwherein the bacillus calmette-guerin has been modified via a clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR associated protein (Cas) system to produce tomatidine.

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