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Methods of treating acute myeloid leukemia with antibodies to bone marrow stromal antigen 1

  • US 9,732,160 B2
  • Filed: 09/23/2015
  • Issued: 08/15/2017
  • Est. Priority Date: 06/28/2011
  • Status: Active Grant
First Claim
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1. A method of treating acute myeloid leukemia (AML) in a patient comprising administering to the patient an antibody, or antigen binding portion thereof, wherein the antibody, or antigen binding portion thereof, comprises a heavy chain variable region CDR1 comprising SEQ ID NO:

  • 10, a heavy chain variable region CDR2 comprising SEQ ID NO;

    12 or SEQ ID NO;

    51, a heavy chain variable region CDR3 comprising SEQ ID NO;

    14, a light chain variable region CDR1 comprising SEQ ID NO;

    16, a light chain variable region CDR2 comprising SEQ ID NO;

    18, and a light chain variable region CDR3 comprising SEQ ID NO;

    20.

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